Optic neuritis due to immunobiologics: first Brazilian case report

The change in immunological response obtained by immunobiologics has brought a new paradigm to the treatment of immune-mediated disorders. As a result of their efficacy, there is a positive impact on the quality of life of patients. However, severe side effects, such as demyelination of cerebral or...

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Main Authors: Luiz Gustavo Martins da Silva, Letícia Soares Sasso, Carlos José Nelli, Fred Bernardes Filho, Marilda Aparecida Milanez Morgado de Abreu
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2013-12-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800162&tlng=en
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author Luiz Gustavo Martins da Silva
Letícia Soares Sasso
Carlos José Nelli
Fred Bernardes Filho
Marilda Aparecida Milanez Morgado de Abreu
author_facet Luiz Gustavo Martins da Silva
Letícia Soares Sasso
Carlos José Nelli
Fred Bernardes Filho
Marilda Aparecida Milanez Morgado de Abreu
author_sort Luiz Gustavo Martins da Silva
collection DOAJ
description The change in immunological response obtained by immunobiologics has brought a new paradigm to the treatment of immune-mediated disorders. As a result of their efficacy, there is a positive impact on the quality of life of patients. However, severe side effects, such as demyelination of cerebral or peripheral nerves, have been reported. After review of literature using PubMed and MEDLINE data from 2000 to 2012, we identified the cases correlating the biological uniterms and optic neuritis. This article reports the first Brazilian optic neuritis case associated with the use of immunobiologics. This publication is justified by the rarity of the disease and atypical therapeutical evolution.
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spelling doaj.art-efaa6119e9b6490d8f93c890752b1a982022-12-22T04:12:49ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962013-12-01886 suppl 116216510.1590/abd1806-4841.20132295Optic neuritis due to immunobiologics: first Brazilian case reportLuiz Gustavo Martins da SilvaLetícia Soares SassoCarlos José NelliFred Bernardes FilhoMarilda Aparecida Milanez Morgado de AbreuThe change in immunological response obtained by immunobiologics has brought a new paradigm to the treatment of immune-mediated disorders. As a result of their efficacy, there is a positive impact on the quality of life of patients. However, severe side effects, such as demyelination of cerebral or peripheral nerves, have been reported. After review of literature using PubMed and MEDLINE data from 2000 to 2012, we identified the cases correlating the biological uniterms and optic neuritis. This article reports the first Brazilian optic neuritis case associated with the use of immunobiologics. This publication is justified by the rarity of the disease and atypical therapeutical evolution.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800162&tlng=enOptic neuritisPsoriasisTumor necrosis factor-alpha
spellingShingle Luiz Gustavo Martins da Silva
Letícia Soares Sasso
Carlos José Nelli
Fred Bernardes Filho
Marilda Aparecida Milanez Morgado de Abreu
Optic neuritis due to immunobiologics: first Brazilian case report
Anais Brasileiros de Dermatologia
Optic neuritis
Psoriasis
Tumor necrosis factor-alpha
title Optic neuritis due to immunobiologics: first Brazilian case report
title_full Optic neuritis due to immunobiologics: first Brazilian case report
title_fullStr Optic neuritis due to immunobiologics: first Brazilian case report
title_full_unstemmed Optic neuritis due to immunobiologics: first Brazilian case report
title_short Optic neuritis due to immunobiologics: first Brazilian case report
title_sort optic neuritis due to immunobiologics first brazilian case report
topic Optic neuritis
Psoriasis
Tumor necrosis factor-alpha
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800162&tlng=en
work_keys_str_mv AT luizgustavomartinsdasilva opticneuritisduetoimmunobiologicsfirstbraziliancasereport
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AT carlosjosenelli opticneuritisduetoimmunobiologicsfirstbraziliancasereport
AT fredbernardesfilho opticneuritisduetoimmunobiologicsfirstbraziliancasereport
AT marildaaparecidamilanezmorgadodeabreu opticneuritisduetoimmunobiologicsfirstbraziliancasereport