A viral nanoparticle with dual function as an anthrax antitoxin and vaccine.

A viral nanoparticle with dual function as an anthrax antitoxin and vaccine.

The recent use of Bacillus anthracis as a bioweapon has stimulated the search for novel antitoxins and vaccines that act rapidly and with minimal adverse effects. B. anthracis produces an AB-type toxin composed of the receptor-binding moiety protective antigen (PA) and the enzymatic moieties edema f...

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Bibliographic Details
Main Authors: Darly J Manayani, Diane Thomas, Kelly A Dryden, Vijay Reddy, Marc E Siladi, John M Marlett, G Jonah A Rainey, Michael E Pique, Heather M Scobie, Mark Yeager, John A T Young, Marianne Manchester, Anette Schneemann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2000967?pdf=render

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