Cough and fever in an immigrant adolescent with abnormal chest X-ray

Tuberculosis (TB) remains a leading cause of death from infectious disease worldwide with 80,000 pediatric deaths annually. Disease caused by Mycobacterium tuberculosis (Mtb) is usually asymptomatic in pediatric patients and resolves after completion of standard therapy with isoniazid (INH). Rare re...

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Main Authors: Nicole Giles, Rajeev Bhatia
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007116301423
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author Nicole Giles
Rajeev Bhatia
author_facet Nicole Giles
Rajeev Bhatia
author_sort Nicole Giles
collection DOAJ
description Tuberculosis (TB) remains a leading cause of death from infectious disease worldwide with 80,000 pediatric deaths annually. Disease caused by Mycobacterium tuberculosis (Mtb) is usually asymptomatic in pediatric patients and resolves after completion of standard therapy with isoniazid (INH). Rare reports document children greater than 10 years of age in endemic regions developing adult type cavitary disease, an infectious pulmonary tuberculosis lesion. This is a notable case of post-infectious pulmonary TB disease with adult type cavitation in an immigrant adolescent, which developed even after completing standard therapy with INH. With increasing immigration of refugees from endemic regions into the United States, the Center for Disease Control implemented standardized testing and treatment of TB. However even with identification of disease, many immigrants may not seek treatment or complete therapy given lack of health insurance, and poor access to health care. This case of a 14 year old adolescent with post primary cavitary TB highlights the importance of directly observed therapy (DOT) and medication compliance. Perhaps as noteworthy, this case also emphasizes the need for pediatricians to recognize the impact on public health and the potential for spread of active TB within schools and the community especially in pulmonary cavitary lesion.
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spelling doaj.art-efab7a8ff1db421b939466a82d09d9e82022-12-22T03:11:37ZengElsevierRespiratory Medicine Case Reports2213-00712017-01-0120C192110.1016/j.rmcr.2016.10.010Cough and fever in an immigrant adolescent with abnormal chest X-rayNicole GilesRajeev BhatiaTuberculosis (TB) remains a leading cause of death from infectious disease worldwide with 80,000 pediatric deaths annually. Disease caused by Mycobacterium tuberculosis (Mtb) is usually asymptomatic in pediatric patients and resolves after completion of standard therapy with isoniazid (INH). Rare reports document children greater than 10 years of age in endemic regions developing adult type cavitary disease, an infectious pulmonary tuberculosis lesion. This is a notable case of post-infectious pulmonary TB disease with adult type cavitation in an immigrant adolescent, which developed even after completing standard therapy with INH. With increasing immigration of refugees from endemic regions into the United States, the Center for Disease Control implemented standardized testing and treatment of TB. However even with identification of disease, many immigrants may not seek treatment or complete therapy given lack of health insurance, and poor access to health care. This case of a 14 year old adolescent with post primary cavitary TB highlights the importance of directly observed therapy (DOT) and medication compliance. Perhaps as noteworthy, this case also emphasizes the need for pediatricians to recognize the impact on public health and the potential for spread of active TB within schools and the community especially in pulmonary cavitary lesion.http://www.sciencedirect.com/science/article/pii/S2213007116301423TuberculosisImmigrantAdolescentPulmonary cavitary lesionDirectly observed therapy
spellingShingle Nicole Giles
Rajeev Bhatia
Cough and fever in an immigrant adolescent with abnormal chest X-ray
Respiratory Medicine Case Reports
Tuberculosis
Immigrant
Adolescent
Pulmonary cavitary lesion
Directly observed therapy
title Cough and fever in an immigrant adolescent with abnormal chest X-ray
title_full Cough and fever in an immigrant adolescent with abnormal chest X-ray
title_fullStr Cough and fever in an immigrant adolescent with abnormal chest X-ray
title_full_unstemmed Cough and fever in an immigrant adolescent with abnormal chest X-ray
title_short Cough and fever in an immigrant adolescent with abnormal chest X-ray
title_sort cough and fever in an immigrant adolescent with abnormal chest x ray
topic Tuberculosis
Immigrant
Adolescent
Pulmonary cavitary lesion
Directly observed therapy
url http://www.sciencedirect.com/science/article/pii/S2213007116301423
work_keys_str_mv AT nicolegiles coughandfeverinanimmigrantadolescentwithabnormalchestxray
AT rajeevbhatia coughandfeverinanimmigrantadolescentwithabnormalchestxray