A new pma1 mutation identified in a chronologically long-lived fission yeast mutant

A new pma1 mutation identified in a chronologically long-lived fission yeast mutant

We isolated a chronologically long-lived mutant of Schizosaccharomyces pombe and found a new mutation in pma1+ that encoded for an essential P-type proton ATPase. An Asp-138 to Asn mutation resulted in reduced Pma1 activity, concomitant with an increase in the chronological lifespan of this fission...

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Bibliographic Details
Main Authors: Chikako Naito, Hirokazu Ito, Tomoko Oshiro, Hokuto Ohtsuka, Hiroshi Murakami, Hirofumi Aiba
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:FEBS Open Bio
Subjects:
Chronological lifespan
Fission yeast
Pma1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211546314000886

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