Clinico-pathological Study of Space Occupying Lesions of Nasal Cavity, Paranasal Sinuses and Nasopharynx
Background: A variety of non-neoplastic and neoplastic lesions of nasal cavity, paranasal sinuses and nasopharynx are commonly encountered in clinical practice. The aim of this study was to study clinical and histopathological profile of space occupying lesions of nasal cavity, paranasal sinuses...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/5150/10662_CE(Ra)_F(Sh)_PF1(AJAK)_PFA(Sh).pdf |
| Summary: | Background: A variety of non-neoplastic and neoplastic
lesions of nasal cavity, paranasal sinuses and nasopharynx
are commonly encountered in clinical practice. The aim of this
study was to study clinical and histopathological profile of
space occupying lesions of nasal cavity, paranasal sinuses and
nasopharynx in a tertiary care hospital of Rajasthan over the
period of January 2013 to January 2014.
Materials and Methods: This was a prospective study of 147
cases (male 100, female 47; age group ranging from less than 1
y to 76 y) of space occupying lesions of nasal cavity, paranasal
sinuses and nasopharynx over the period of 12 months (from
January 2013 to January 2014). All tissues after fixation in 10%
buffered formalin, processed and then stained with Hematoxylin
& Eosin to study various histopathological patterns.
Results: These 147 cases were broadly categorized in two
categories, one category as nasal and paranasal sinus masses
and the other as nasopharyngeal masses with 91 and 56 cases,
respectively. These lesions were common in second and third
decades of life with male predominance. Among nasal and
paranasal sinus masses, there were 67 (73.6%) non-neoplastic
and 24 (26.4%) neoplastic lesions. Inflammatory polyps (89.5%)
were the most common among the non-neoplastic masses;
Inverted papilloma (45.46%) the most common among the
benign neoplastic and squamous cell carcinoma (46.15%) was
the commonest out of all malignant masses.
Out of 56 nasopharyngeal masses, there were 53 (94.6%) non
neoplastic and 3 (5.4%) neoplastic lesions. Majority of these i.e.
52 cases were of adenotonsillar hypertrophy.
Conclusion: We concluded that complete clinical, radiological
and histopathological correlation helps us to categorize these
sinonasal lesions into various non-neoplastic and neoplastic
types. But final histopathological examination provides a
confirmatory diagnosis, although Immunohistochemistry is the
final diagnostic method in few cases. |
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| ISSN: | 2249-782X 0973-709X |