IL-33/ST2 Axis Plays a Protective Effect in <i>Streptococcus pyogenes</i> Infection through Strengthening of the Innate Immunity

IL-33/ST2 Axis Plays a Protective Effect in <i>Streptococcus pyogenes</i> Infection through Strengthening of the Innate Immunity

Group A <i>Streptococcus</i> (GAS) causes invasive human diseases with the cytokine storm. Interleukin-33 (IL-33)/suppression of tumorigenicity 2 (ST2) axis is known to drive T<sub>H</sub>2 response, while its effect on GAS infection is unclear. We used an air pouch model to...

Full description

Bibliographic Details
Main Authors:	Chih-Feng Kuo, Wei-Yu Chen, Hai-Han Yu, Yu-Hsuan Tsai, Ya-Chu Chang, Chih-Peng Chang, Nina Tsao
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	International Journal of Molecular Sciences
Subjects:	interleukin-33 (IL-33) suppression of tumorigenicity 2 (ST2) Group A <i>Streptococcus</i> (GAS) the innate immunity
Online Access:	https://www.mdpi.com/1422-0067/22/19/10566

Similar Items

The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin
by: Manoussa Fanny, et al.
Published: (2018-06-01)

Louki Zupa decoction attenuates the airway inflammation in acute asthma mice induced by ovalbumin through IL-33/ST2-NF-κB/GSK3β/mTOR signalling pathway
by: Xi Huang, et al.
Published: (2022-12-01)

Correlation Profile of Suppression of Tumorigenicity 2 and/or Interleukin-33 with Biomarkers in the Adipose Tissue of Individuals with Different Metabolic States
by: Hasan A, et al.
Published: (2020-10-01)

Dual roles of interleukin-33 in cognitive function by regulating central nervous system inflammation
by: Xiuqin Rao, et al.
Published: (2022-08-01)

Evaluation of serum interleukin-33 and soluble suppression of tumorigenicity 2 (sST2) receptors in patients with and without periodontal disease
by: Himadri Singh, et al.
Published: (2022-01-01)

The IL-33/ST2 Axis in Immune Responses Against Parasitic Disease: Potential Therapeutic Applications
by: Nathan Ryan, et al.
Published: (2020-04-01)

<i>Helicobacter pylori</i> Induces IL-33 Production and Recruits ST-2 to Lipid Rafts to Exacerbate Inflammation
by: Chia-Jung Kuo, et al.
Published: (2019-10-01)

Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells
by: Hiroko Hayakawa, et al.
Published: (2016-03-01)

Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk
by: Junting Huang, et al.
Published: (2020-10-01)

Predicting Immuno-Metabolic Complications After Allogeneic Hematopoietic Cell Transplant with the Cytokine Interleukin-33 (IL-33) and its Receptor Serum-Stimulation 2 (ST2)
by: Uttam K. Rao, et al.
Published: (2020-05-01)

Interference of LPS <i>H. pylori</i> with IL-33-Driven Regeneration of <i>Caviae porcellus</i> Primary Gastric Epithelial Cells and Fibroblasts
by: Weronika Gonciarz, et al.
Published: (2021-06-01)

IL-33 at the Crossroads of Metabolic Disorders and Immunity
by: Lei Tu, et al.
Published: (2019-01-01)

IL-33 Alarmin and Its Active Proinflammatory Fragments Are Released in Small Intestine in Celiac Disease
by: Federico Perez, et al.
Published: (2020-10-01)

The ST2/IL-33 Pathway in Adult and Paediatric Heart Disease and Transplantation
by: Giacomina Brunetti, et al.
Published: (2023-06-01)

The serum levels and clinical significance of interleukin-33 and soluble ST2 in patients with vitiligo
by: Li YANG, et al.
Published: (2020-12-01)

IL33 and Mast Cells—The Key Regulators of Immune Responses in Gastrointestinal Cancers?
by: Moritz F. Eissmann, et al.
Published: (2020-07-01)

The Paradigm Change of IL-33 in Vascular Biology
by: Svitlana Demyanets, et al.
Published: (2021-12-01)

Contribution of IL-33 to the Pathogenesis of Colorectal Cancer
by: Guanglin Cui, et al.
Published: (2018-11-01)

Blockade of IL‐33 signalling attenuates osteoarthritis
by: Zengliang He, et al.
Published: (2020-01-01)

Interleukin 33 Selectively Augments Rhinovirus-Induced Type 2 Immune Responses in Asthmatic but not Healthy People
by: Lisa M. Jurak, et al.
Published: (2018-08-01)

House Dust Mite Induces Bone Marrow IL-33-Responsive ILC2s and T<sub>H</sub> Cells
by: Emma Boberg, et al.
Published: (2020-05-01)

IL-33 in Rheumatic Diseases
by: Yuanji Dong, et al.
Published: (2021-09-01)

Serum levels of Interleukin-33 and its soluble receptor ST2 in asthmatic patients
by: Ensaf A. Azazi, et al.
Published: (2014-04-01)

Interleukin‐33 increases type 2 innate lymphoid cell count and their activation in eosinophilic asthma
by: Fengfei Sun, et al.
Published: (2023-06-01)

IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition
by: Wen-jia Lei, et al.
Published: (2023-07-01)

An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice
by: D.A.C. Magro, et al.
Published: (2013-08-01)

Innate-Type and Acquired-Type Allergy Regulated by IL-33
by: Tomohiro Yoshimoto, et al.
Published: (2014-01-01)

Interleukin-33 in Systemic Sclerosis: Expression and Pathogenesis
by: Liya Li, et al.
Published: (2018-11-01)

Biomarkers ST2 and interleukin 33 for assessing the severity of cardiac inflammation and fibrosis in patients with chronic heart failure
by: O. M. Drapkina, et al.
Published: (2021-10-01)

Significance of interleukin-33 and its related cytokines in patients with breast cancers
by: Jing eLiu, et al.
Published: (2014-04-01)

3,3′-Diindolylmethane (DIM): A Potential Therapeutic Agent against Cariogenic <i>Streptococcus mutans</i> Biofilm
by: Yifat Baruch, et al.
Published: (2023-06-01)

Osthole alleviates food allergy by blocking IL-33/ST2 pathway and targeting ILC2-CD4+T response
by: Lei Wang, et al.
Published: (2023-09-01)

Regulatory Mechanisms of IL-33-ST2-Mediated Allergic Inflammation
by: Hiroaki Takatori, et al.
Published: (2018-09-01)

Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response
by: Takahiro Kawauchi, et al.
Published: (2017-07-01)

IL-33/ST2 immunobiology in coronary artery disease: A systematic review and meta-analysis
by: Renli Liu, et al.
Published: (2022-10-01)

IL-33-induced keratoconjunctivitis is mediated by group 2 innate lymphoid cells in mice
by: Yuka Hosotani, et al.
Published: (2023-04-01)

Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans
by: Keigo Ueno, et al.
Published: (2023-10-01)

The Effects of Vitamin D on the Expression of IL-33 and Its Receptor ST2 in Skin Cells; Potential Implication for Psoriasis
by: Justyna M. Wierzbicka, et al.
Published: (2021-11-01)

Understanding Interleukin 33 and Its Roles in Eosinophil Development
by: Paul J. Bryce, et al.
Published: (2017-05-01)

Dual Immune Regulatory Roles of Interleukin-33 in Pathological Conditions
by: Han Guo, et al.
Published: (2022-10-01)