Mechanism of negative modulation of FSH signaling by salt-inducible kinases in rat granulosa cells

Mechanism of negative modulation of FSH signaling by salt-inducible kinases in rat granulosa cells

The optimal development of preovulatory follicles needs follicle-stimulating hormone (FSH). Recent findings revealed that salt-inducible kinases (SIKs) inhibit FSH actions in humans and rodents. This report seeks to increase our understanding of the molecular mechanisms controlled by SIKs that parti...

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Bibliographic Details
Main Authors: Marah Armouti, Miriam Rodriguez-Esquivel, Carlos Stocco
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
ovary
granulosa cells
SIKs
CREB
CRTC2
steroidogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1026358/full

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