Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer
Pancreatic cancer is one of the leading causes off cancer-related deaths globally. In Europe, this type of cancer has the lowest survival rate of all cancers. A majority of patients have unresectable or even metastatic disease. In addition, actual therapeutic options are not curative, and surgical t...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/15/23/5577 |
| _version_ | 1797400423567458304 |
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| author | Miłosz Caban Ewa Małecka-Wojciesko |
| author_facet | Miłosz Caban Ewa Małecka-Wojciesko |
| author_sort | Miłosz Caban |
| collection | DOAJ |
| description | Pancreatic cancer is one of the leading causes off cancer-related deaths globally. In Europe, this type of cancer has the lowest survival rate of all cancers. A majority of patients have unresectable or even metastatic disease. In addition, actual therapeutic options are not curative, and surgical treatment is associated with high post-operative morbidity and a lack of uniform translation of surgical success into long-term survival. Moreover, there is no screening for the general population which is recommended, and the overall poor prognosis in pancreatic cancer is related to late clinical detection. Therefore, early diagnosis and early treatment of pancreatic cancer are particularly critical. In this review, we summarize the most significant gaps and opportunities in the diagnosis and treatment of pancreatic cancer to emphasize need for improvement of early detection and the therapeutic efficacy of the available treatment for this cancer. Novel, inclusive, and intentional research is needed to produce improvements in pancreatic cancer in mm the world. |
| first_indexed | 2024-03-09T01:54:19Z |
| format | Article |
| id | doaj.art-efb370cf19eb44138cccfa9f5969ee73 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T01:54:19Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-efb370cf19eb44138cccfa9f5969ee732023-12-08T15:12:35ZengMDPI AGCancers2072-66942023-11-011523557710.3390/cancers15235577Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic CancerMiłosz Caban0Ewa Małecka-Wojciesko1Department of Digestive Tract Diseases, Medical University of Lodz, 90-153 Lodz, PolandDepartment of Digestive Tract Diseases, Medical University of Lodz, 90-153 Lodz, PolandPancreatic cancer is one of the leading causes off cancer-related deaths globally. In Europe, this type of cancer has the lowest survival rate of all cancers. A majority of patients have unresectable or even metastatic disease. In addition, actual therapeutic options are not curative, and surgical treatment is associated with high post-operative morbidity and a lack of uniform translation of surgical success into long-term survival. Moreover, there is no screening for the general population which is recommended, and the overall poor prognosis in pancreatic cancer is related to late clinical detection. Therefore, early diagnosis and early treatment of pancreatic cancer are particularly critical. In this review, we summarize the most significant gaps and opportunities in the diagnosis and treatment of pancreatic cancer to emphasize need for improvement of early detection and the therapeutic efficacy of the available treatment for this cancer. Novel, inclusive, and intentional research is needed to produce improvements in pancreatic cancer in mm the world.https://www.mdpi.com/2072-6694/15/23/5577early detectionmorbiditymortalitypancreatic cancerpancreatic ductal adenocarcinomascreening |
| spellingShingle | Miłosz Caban Ewa Małecka-Wojciesko Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer Cancers early detection morbidity mortality pancreatic cancer pancreatic ductal adenocarcinoma screening |
| title | Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer |
| title_full | Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer |
| title_fullStr | Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer |
| title_full_unstemmed | Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer |
| title_short | Gaps and Opportunities in the Diagnosis and Treatment of Pancreatic Cancer |
| title_sort | gaps and opportunities in the diagnosis and treatment of pancreatic cancer |
| topic | early detection morbidity mortality pancreatic cancer pancreatic ductal adenocarcinoma screening |
| url | https://www.mdpi.com/2072-6694/15/23/5577 |
| work_keys_str_mv | AT miłoszcaban gapsandopportunitiesinthediagnosisandtreatmentofpancreaticcancer AT ewamałeckawojciesko gapsandopportunitiesinthediagnosisandtreatmentofpancreaticcancer |