Dickkopf 3—A New Indicator for the Deterioration of Allograft Function After Kidney Transplantation

Dickkopf 3—A New Indicator for the Deterioration of Allograft Function After Kidney Transplantation

Evidence of tubular atrophy and interstitial fibrosis is prognostically unfavorable and associated with a premature graft loss after kidney transplantation. Recently, Dickkopf 3 (DKK3), a profibrotic glycoprotein released by stressed tubular epithelial cells, has been identified to cause IF/TA by re...

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Bibliographic Details
Main Authors: Antonia Schuster, Louisa Steines, Karolina Müller, Florian Zeman, Peter Findeisen, Bernhard Banas, Tobias Bergler
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Medicine
Subjects:
kidney transplantation
allograft survival
Dickkopf (DKK)
albuminuria
glomerular filtration rate
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.885018/full

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