The Specific Copper(II) Chelator TDMQ20 Is Efficient for the Treatment of Wilson’s Disease in Mice

The Specific Copper(II) Chelator TDMQ20 Is Efficient for the Treatment of Wilson’s Disease in Mice

(1) Background: In patients with Wilson’s disease, the deficiency of the copper carrier ATP7B causes the accumulation of copper in the liver, brain and various other organs. Lifelong treatment is therefore mandatory, using copper chelators to increase the excretion of copper and to avoid life-threat...

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Bibliographic Details
Main Authors: Yingshan Zhu, Ying Tang, Lan Huang, Michel Nguyen, Yan Liu, Anne Robert, Bernard Meunier
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
copper chelator
liver
toxic milk mouse
Wilson’s disease
Online Access:https://www.mdpi.com/1999-4923/15/12/2719

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