Anti-dsDNA B-Cell ELISpot as a Monitoring and Flare Prediction Tool in SLE Patients

Anti-dsDNA B-Cell ELISpot as a Monitoring and Flare Prediction Tool in SLE Patients

Anti-dsDNA autoantibodies quantification and complement levels are widely used to monitor disease activity in systemic lupus erythematosus (SLE). However, better biomarkers are still needed. We hypothesised whether the dsDNA antibody-secreting B-cells could be a complementary biomarker in disease ac...

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Bibliographic Details
Main Authors: Albert Pérez-Isidro, Marc Xipell, Arturo Llobell, Noemí De Moner, Gema M. Lledó, Ricard Cervera, Sergio Prieto-González, Luis F. Quintana, Gerard Espinosa, Mila García-Ormaechea, Estíbaliz Ruiz-Ortiz, Odette Viñas
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Clinical Medicine
Subjects:
systemic lupus erythematosus
SLE biomarkers
SLE nephritis
SLE disease activity
antibody secreting cells ELISpot
anti-dsDNA autoantibodies
Online Access:https://www.mdpi.com/2077-0383/12/4/1295

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