The Role of Sleep Deprivation in Arrhythmias

Sleep is essential to the normal psychological and physiological activities of the human body. Increasing evidence indicates that sleep deprivation is associated with the occurrence, development, and poor treatment effects of various arrhythmias. Sleep deprivation affects not only the peripheral ner...

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Bibliographic Details
Main Authors: Wenlong Wang, Hongpeng Yin, Ge Sun, Junpei Zhang, Jingmei Sun, Nadine Mbabazi, Lina Zou, Bin Li, Pengqi Lin, Quanwei Pei, Xin Wang, Penghe Wang, Xuanrui Ji, Xiufen Qu, Dechun Yin
Format: Article
Language:English
Published: Compuscript Ltd 2022-09-01
Series:Cardiovascular Innovations and Applications
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2022.0013
Description
Summary:Sleep is essential to the normal psychological and physiological activities of the human body. Increasing evidence indicates that sleep deprivation is associated with the occurrence, development, and poor treatment effects of various arrhythmias. Sleep deprivation affects not only the peripheral nervous system but also the central nervous system, which regulates the occurrence of arrhythmias. In addition, sleep deprivation is associated with apoptotic pathways, mitochondrial energy metabolism disorders, and immune system dysfunction. Although studies increasingly suggest that pathological sleep patterns are associated with various atrial and ventricular arrhythmias, further research is needed to identify specific mechanisms and recommend therapeutic interventions. This review summarizes the findings of sleep deprivation in animal experiments and clinical studies, current challenges, and future research directions in the field of arrhythmias.
ISSN:2009-8618
2009-8782