A modified graft‐versus‐host‐induced model for systemic sclerosis, with pulmonary fibrosis in Rag2‐deficient mice

A modified graft‐versus‐host‐induced model for systemic sclerosis, with pulmonary fibrosis in Rag2‐deficient mice

Systemic sclerosis (SSc) is a connective tissue disease that results in fibrosis in multiple organs. Various animal models for this disease have been developed, both genetic and induced. One of the induced models, sclerodermatous graft‐versus‐host disease (scl‐GvHD), exhibits the main characteristic...

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Bibliographic Details
Main Authors: Xue Yang, Chi Liu, Masayuki Fujino, Ji Yang, Xiao‐Kang Li, Hejian Zou
Format: Article
Language:English
Published: Wiley 2017-09-01
Series:FEBS Open Bio
Subjects:
fibrosis
graft‐versus‐host disease
systemic sclerosis
Online Access:https://doi.org/10.1002/2211-5463.12268

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