Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study
Purpose: This study was conducted to assess the intraocular pressure (IOP) control and postoperative complications following a non-valved glaucoma drainage device (GDD) surgery in refractory glaucoma. Methods: This was a prospective interventional study conducted on patients with glaucoma refractory...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022-01-01
|
| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=12;spage=4212;epage=4216;aulast=Jayasri |
| _version_ | 1798006486839853056 |
|---|---|
| author | P Jayasri Subashini Kaliaperumal Geeta Behera Mary Stephen |
| author_facet | P Jayasri Subashini Kaliaperumal Geeta Behera Mary Stephen |
| author_sort | P Jayasri |
| collection | DOAJ |
| description | Purpose: This study was conducted to assess the intraocular pressure (IOP) control and postoperative complications following a non-valved glaucoma drainage device (GDD) surgery in refractory glaucoma. Methods: This was a prospective interventional study conducted on patients with glaucoma refractory to maximal medications or failed surgical treatment who underwent Aurolab aqueous drainage implant (AADI; Aurolabs, India) surgery. Primary outcome measures were IOP control, postoperative complications, and reduction in the number of antiglaucoma medications (AGM). Results: Thirty-four eyes were analyzed and the mean follow-up was 16.06 ± 5.63 months. The preoperative median (Q1, Q3) IOP was 31 mmHg (28, 36.5) which decreased to 12 mmHg (12, 14) at 6 months postoperatively. The median (Q1, Q3) number of AGMs decreased from 3 (3, 4) to 0 (0, 1). Significant complications like implant extrusion and tube exposure were noted in two eyes. The total success and failure rates at 6 months were 91.1% and 8.8%, respectively. Conclusion: AADI is effective in achieving target IOP and significantly reduces the use of AGMs with good safety in the short term. Long-term follow-up studies are needed to assess long-term IOP control and cost-effectiveness. |
| first_indexed | 2024-04-11T12:56:37Z |
| format | Article |
| id | doaj.art-efbeedf670ee47d6bd70e915c9b1f6ef |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-11T12:56:37Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-efbeedf670ee47d6bd70e915c9b1f6ef2022-12-22T04:23:04ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-0170124212421610.4103/ijo.IJO_1391_22Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective studyP JayasriSubashini KaliaperumalGeeta BeheraMary StephenPurpose: This study was conducted to assess the intraocular pressure (IOP) control and postoperative complications following a non-valved glaucoma drainage device (GDD) surgery in refractory glaucoma. Methods: This was a prospective interventional study conducted on patients with glaucoma refractory to maximal medications or failed surgical treatment who underwent Aurolab aqueous drainage implant (AADI; Aurolabs, India) surgery. Primary outcome measures were IOP control, postoperative complications, and reduction in the number of antiglaucoma medications (AGM). Results: Thirty-four eyes were analyzed and the mean follow-up was 16.06 ± 5.63 months. The preoperative median (Q1, Q3) IOP was 31 mmHg (28, 36.5) which decreased to 12 mmHg (12, 14) at 6 months postoperatively. The median (Q1, Q3) number of AGMs decreased from 3 (3, 4) to 0 (0, 1). Significant complications like implant extrusion and tube exposure were noted in two eyes. The total success and failure rates at 6 months were 91.1% and 8.8%, respectively. Conclusion: AADI is effective in achieving target IOP and significantly reduces the use of AGMs with good safety in the short term. Long-term follow-up studies are needed to assess long-term IOP control and cost-effectiveness.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=12;spage=4212;epage=4216;aulast=Jayasriaurolab aqueous drainage implant (aadi)glaucoma drainage deviceglaucoma surgeryintraocular pressure (iop)refractory glaucoma |
| spellingShingle | P Jayasri Subashini Kaliaperumal Geeta Behera Mary Stephen Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study Indian Journal of Ophthalmology aurolab aqueous drainage implant (aadi) glaucoma drainage device glaucoma surgery intraocular pressure (iop) refractory glaucoma |
| title | Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study |
| title_full | Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study |
| title_fullStr | Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study |
| title_full_unstemmed | Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study |
| title_short | Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study |
| title_sort | safety and efficacy of aurolab aqueous drainage implant in refractory glaucoma a prospective study |
| topic | aurolab aqueous drainage implant (aadi) glaucoma drainage device glaucoma surgery intraocular pressure (iop) refractory glaucoma |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=12;spage=4212;epage=4216;aulast=Jayasri |
| work_keys_str_mv | AT pjayasri safetyandefficacyofaurolabaqueousdrainageimplantinrefractoryglaucomaaprospectivestudy AT subashinikaliaperumal safetyandefficacyofaurolabaqueousdrainageimplantinrefractoryglaucomaaprospectivestudy AT geetabehera safetyandefficacyofaurolabaqueousdrainageimplantinrefractoryglaucomaaprospectivestudy AT marystephen safetyandefficacyofaurolabaqueousdrainageimplantinrefractoryglaucomaaprospectivestudy |