Colon Cancer-Related Genes Identification and Function Study Based on Single-Cell Multi-Omics Integration

Colon Cancer-Related Genes Identification and Function Study Based on Single-Cell Multi-Omics Integration

Transcriptomes and DNA methylation of colon cancer at the single-cell level are used to identify marker genes and improve diagnoses and therapies. Seven colon cancer subtypes are recognized based on the single-cell RNA sequence, and the differentially expressed genes regulated by dysregulated methyl...

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Bibliographic Details
Main Authors: Xuepu Sun, Yu Guo, Yu Zhang, Peng Zhao, Zhaoqing Wang, Zheng Wei, Haiquan Qiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
colon cancer
single cell
transcriptome
methylation
comprehensive analysis
marker genes
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.789587/full

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