Gamma-tocotrienol modifies methylation of HOXA10, IRF4 and RORα genes in CD4+ T-lymphocytes: Evidence from a syngeneic mouse model of breast cancer

Gamma-tocotrienol modifies methylation of HOXA10, IRF4 and RORα genes in CD4+ T-lymphocytes: Evidence from a syngeneic mouse model of breast cancer

DNA methylation plays a crucial role in polarising naïve lymphocytes towards their various sub-populations to fight against many immune challenges including establishment of tumour. Gamma-tocotrienol (γT3) is a natural form of vitamin E, reported to possess anticancer and immunomodulatory effects. T...

Full description

Bibliographic Details
Main Authors: Ammu K. Radhakrishnan, Jeya Seela Anandha Rao, Shonia Subramaniam, Premdass Ramdas
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Immunology
Subjects:
Gamma-tocotrienol
DNA methylation
Breast cancer
CD4+ T-lymphocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S2590255521000184

Similar Items

Similar Items