From biomarkers to a clue of biology: a computation-aided perspective of immune gene expression profiles in human type 1 diabetes
Dysregulated expression of key immune genes may cause breakdown of immunological tolerance and development of autoimmune disorders such as type 1 diabetes (T1D). General immune insufficiencies have also been implicated as a trigger of autoimmunity, due to their potential impact on immune homeostasis...
Main Authors: | Dongmei eHan, Xiaodong eCai, Ji eWen, Norma eKenyon, Zhibin eChen |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00320/full |
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