Novel discovery of schisandrin A regulating the interplay of autophagy and apoptosis in oligoasthenospermia by targeting SCF/c-kit and TRPV1 via biosensors

Novel discovery of schisandrin A regulating the interplay of autophagy and apoptosis in oligoasthenospermia by targeting SCF/c-kit and TRPV1 via biosensors

Oligoasthenospermia is the primary cause of infertility. However, there are still enormous challenges in the screening of critical candidates and targets of oligoasthenospermia owing to its complex mechanism. In this study, stem cell factor (SCF), c-kit, and transient receptor potential vanilloid 1...

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Bibliographic Details
Main Authors: Lijuan Ma, Boyi Li, Jinchen Ma, Chunyuan Wu, Nan Li, Kailin Zhou, Yun Yan, Mingshuang Li, Xiaoyan Hu, Hao Yan, Qi Wang, Yanfei Zheng, Zhisheng Wu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Oligoasthenospermia
Male infertility
Autophagy
Apoptosis
Biosensor
Schisandrin A.
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523000047

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