A Random Forests Framework for Modeling Haplotypes as Mosaics of Reference Haplotypes

Many genomic data analyses such as phasing, genotype imputation, or local ancestry inference share a common core task: matching pairs of haplotypes at any position along the chromosome, thereby inferring a target haplotype as a succession of pieces from reference haplotypes, commonly called a mosaic...

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Bibliographic Details
Main Authors: Pierre Faux, Pierre Geurts, Tom Druet
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00562/full