Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study
Abstract Cross-sectional relationships between nocturia and sleep problems have been well evaluated but the risk association for each incidence is scarcely reported. This analysis included 8076 participants of the Nagahama study in Japan (median age 57, 31.0% male) and associations between nocturia...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-36707-y |
| _version_ | 1797801541551259648 |
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| author | Hiromitsu Negoro Kazuya Setoh Arinobu Fukunaga Takahisa Kawaguchi Satoshi Funada Takayuki Yoshino Koji Yoshimura Bryan J. Mathis Yasuharu Tabara Fumihiko Matsuda Osamu Ogawa Takashi Kobayashi |
| author_facet | Hiromitsu Negoro Kazuya Setoh Arinobu Fukunaga Takahisa Kawaguchi Satoshi Funada Takayuki Yoshino Koji Yoshimura Bryan J. Mathis Yasuharu Tabara Fumihiko Matsuda Osamu Ogawa Takashi Kobayashi |
| author_sort | Hiromitsu Negoro |
| collection | DOAJ |
| description | Abstract Cross-sectional relationships between nocturia and sleep problems have been well evaluated but the risk association for each incidence is scarcely reported. This analysis included 8076 participants of the Nagahama study in Japan (median age 57, 31.0% male) and associations between nocturia and self-reported, sleep-related problems (poor sleep) were evaluated cross-sectionally. Causal effects on each new-onset case were analyzed longitudinally after 5 years. Three models were applied: univariable analysis, adjustment for basic variables (i.e., demographic and lifestyle variables) and full adjustment for basic and clinical variables. The overall prevalences of poor sleep and nocturia were 18.6% and 15.5%, while poor sleep was positively associated with nocturia (OR = 1.85, p < 0.001) and vice versa (OR = 1.90, p < 0.001). Among 6579 good sleep participants, 18.5% developed poor sleep. Baseline nocturia was positively associated with this incident poor sleep (OR = 1.49, p < 0.001, full adjustment). Among 6824 non-nocturia participants, the nocturia incidence was 11.3%. Baseline poor sleep was positively associated with this incident nocturia (OR = 1.26, p = 0.026); such associations were significant only in women (OR = 1.44, p = 0.004) and under-50-year-old groups (OR = 2.82, p < 0.001), after full adjustment. Nocturia and poor sleep associate with each other. Baseline nocturia can induce new-onset poor sleep while baseline poor sleep may induce new-onset nocturia only in women. |
| first_indexed | 2024-03-13T04:52:03Z |
| format | Article |
| id | doaj.art-efd010f71799475b9db5da681db99c56 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-13T04:52:03Z |
| publishDate | 2023-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-efd010f71799475b9db5da681db99c562023-06-18T11:11:27ZengNature PortfolioScientific Reports2045-23222023-06-011311710.1038/s41598-023-36707-yRisk analyses of nocturia on incident poor sleep and vice versa: the Nagahama studyHiromitsu Negoro0Kazuya Setoh1Arinobu Fukunaga2Takahisa Kawaguchi3Satoshi Funada4Takayuki Yoshino5Koji Yoshimura6Bryan J. Mathis7Yasuharu Tabara8Fumihiko Matsuda9Osamu Ogawa10Takashi Kobayashi11Department of Urology, University of TsukubaCenter for Genomic Medicine, Kyoto University Graduate School of MedicineDepartment of Urology, Kyoto University Graduate School of MedicineCenter for Genomic Medicine, Kyoto University Graduate School of MedicineDepartment of Urology, Kyoto University Graduate School of MedicineDepartment of Urology, University of TsukubaDepartment of Urology, Shizuoka General HospitalInternational Medical Center, University of Tsukuba Affiliated HospitalCenter for Genomic Medicine, Kyoto University Graduate School of MedicineCenter for Genomic Medicine, Kyoto University Graduate School of MedicineDepartment of Urology, Kyoto University Graduate School of MedicineDepartment of Urology, Kyoto University Graduate School of MedicineAbstract Cross-sectional relationships between nocturia and sleep problems have been well evaluated but the risk association for each incidence is scarcely reported. This analysis included 8076 participants of the Nagahama study in Japan (median age 57, 31.0% male) and associations between nocturia and self-reported, sleep-related problems (poor sleep) were evaluated cross-sectionally. Causal effects on each new-onset case were analyzed longitudinally after 5 years. Three models were applied: univariable analysis, adjustment for basic variables (i.e., demographic and lifestyle variables) and full adjustment for basic and clinical variables. The overall prevalences of poor sleep and nocturia were 18.6% and 15.5%, while poor sleep was positively associated with nocturia (OR = 1.85, p < 0.001) and vice versa (OR = 1.90, p < 0.001). Among 6579 good sleep participants, 18.5% developed poor sleep. Baseline nocturia was positively associated with this incident poor sleep (OR = 1.49, p < 0.001, full adjustment). Among 6824 non-nocturia participants, the nocturia incidence was 11.3%. Baseline poor sleep was positively associated with this incident nocturia (OR = 1.26, p = 0.026); such associations were significant only in women (OR = 1.44, p = 0.004) and under-50-year-old groups (OR = 2.82, p < 0.001), after full adjustment. Nocturia and poor sleep associate with each other. Baseline nocturia can induce new-onset poor sleep while baseline poor sleep may induce new-onset nocturia only in women.https://doi.org/10.1038/s41598-023-36707-y |
| spellingShingle | Hiromitsu Negoro Kazuya Setoh Arinobu Fukunaga Takahisa Kawaguchi Satoshi Funada Takayuki Yoshino Koji Yoshimura Bryan J. Mathis Yasuharu Tabara Fumihiko Matsuda Osamu Ogawa Takashi Kobayashi Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study Scientific Reports |
| title | Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study |
| title_full | Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study |
| title_fullStr | Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study |
| title_full_unstemmed | Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study |
| title_short | Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study |
| title_sort | risk analyses of nocturia on incident poor sleep and vice versa the nagahama study |
| url | https://doi.org/10.1038/s41598-023-36707-y |
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