Endothelial nitric oxide synthase-derived nitric oxide in the regulation of metabolism [version 1; peer review: 3 approved]

Nitric oxide is an endogenously formed gas that acts as a signaling molecule in the human body. The signaling functions of nitric oxide are accomplished through two primer mechanisms: cGMP-mediated phosphorylation and the formation of S-nitrosocysteine on proteins. This review presents and discusses...

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Bibliographic Details
Main Authors: Margarita Tenopoulou, Paschalis-Thomas Doulias
Format: Article
Language:English
Published: F1000 Research Ltd 2020-10-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-1190/v1
Description
Summary:Nitric oxide is an endogenously formed gas that acts as a signaling molecule in the human body. The signaling functions of nitric oxide are accomplished through two primer mechanisms: cGMP-mediated phosphorylation and the formation of S-nitrosocysteine on proteins. This review presents and discusses previous and more recent findings documenting that nitric oxide signaling regulates metabolic activity. These discussions primarily focus on endothelial nitric oxide synthase (eNOS) as the source of nitric oxide.
ISSN:2046-1402