Analysis of necroptotic proteins in failing human hearts

Analysis of necroptotic proteins in failing human hearts

Abstract Background Cell loss and subsequent deterioration of contractile function are hallmarks of chronic heart failure (HF). While apoptosis has been investigated as a participant in the progression of HF, it is unlikely that it accounts for the total amount of non-functional tissue. In addition,...

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Bibliographic Details
Main Authors: Adrián Szobi, Eva Gonçalvesová, Zoltán V. Varga, Przemyslaw Leszek, Mariusz Kuśmierczyk, Michal Hulman, Ján Kyselovič, Péter Ferdinandy, Adriana Adameová
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Translational Medicine
Subjects:
Heart failure
Cell death
Necroptosis
MLKL
Online Access:http://link.springer.com/article/10.1186/s12967-017-1189-5

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