Mast Cell-Specific Deletion of Group III Secreted Phospholipase A<sub>2</sub> Impairs Mast Cell Maturation and Functions

Mast Cell-Specific Deletion of Group III Secreted Phospholipase A<sub>2</sub> Impairs Mast Cell Maturation and Functions

Tissue-resident mast cells (MCs) have important roles in IgE-associated and -independent allergic reactions. Although microenvironmental alterations in MC phenotypes affect the susceptibility to allergy, understanding of the regulation of MC maturation is still incomplete. We previously reported tha...

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Bibliographic Details
Main Authors: Yoshitaka Taketomi, Yuki Endo, Takayoshi Higashi, Remi Murase, Tomio Ono, Choji Taya, Tetsuyuki Kobayashi, Makoto Murakami
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
mast cells
phospholipase A<sub>2</sub>
lipid mediator
anaphylaxis
contact dermatitis
Online Access:https://www.mdpi.com/2073-4409/10/7/1691

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