The AGMK1-9T7 cell model of neoplasia: Evolution of DNA copy-number aberrations and miRNA expression during transition from normal to metastatic cancer cells

The AGMK1-9T7 cell model of neoplasia: Evolution of DNA copy-number aberrations and miRNA expression during transition from normal to metastatic cancer cells

To study neoplasia in tissue culture, cell lines representing the evolution of normal cells to tumor cells are needed. To produce such cells, we developed the AGMK1-9T7 cell line, established cell banks at 10-passage intervals, and characterized their biological properties. Here we examine the evolu...

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Bibliographic Details
Main Authors: Andrew M. Lewis, Rachael Thomas, Matthew Breen, Keith Peden, Belete Teferedegne, Gideon Foseh, Alison Motsinger-Reif, Daniel Rotroff, Gladys Lewis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9591059/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9591059/?tool=EBI

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