Molecular basis of β-lactam antibiotic resistance of ESKAPE bacterium E. faecium Penicillin Binding Protein PBP5

Molecular basis of β-lactam antibiotic resistance of ESKAPE bacterium E. faecium Penicillin Binding Protein PBP5

Abstract Penicillin-binding proteins (PBPs) are essential for the formation of the bacterial cell wall. They are also the targets of β-lactam antibiotics. In Enterococcus faecium, high levels of resistance to β-lactams are associated with the expression of PBP5, with higher levels of resistance asso...

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Bibliographic Details
Main Authors: Yamanappa Hunashal, Ganesan Senthil Kumar, Meng S. Choy, Éverton D. D’Andréa, Andre Da Silva Santiago, Marta V. Schoenle, Charlene Desbonnet, Michel Arthur, Louis B. Rice, Rebecca Page, Wolfgang Peti
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39966-5

Internet

https://doi.org/10.1038/s41467-023-39966-5

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