Opioid-free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy: a randomized controlled trial
Abstract Background Anesthesia with opioids negatively affects patients’ quality of recovery. Opioid-free anesthesia attempts to avoid these effects. This study aimed to evaluate the effect of opioid-free anesthesia on the quality of recovery, using lidocaine on patients undergoing hysteroscopy. Met...
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | BMC Anesthesiology |
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| Online Access: | https://doi.org/10.1186/s12871-023-02152-7 |
| _version_ | 1797811376713891840 |
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| author | NH Cha Y Hu GH Zhu X Long JJ Jiang Yuan Gong |
| author_facet | NH Cha Y Hu GH Zhu X Long JJ Jiang Yuan Gong |
| author_sort | NH Cha |
| collection | DOAJ |
| description | Abstract Background Anesthesia with opioids negatively affects patients’ quality of recovery. Opioid-free anesthesia attempts to avoid these effects. This study aimed to evaluate the effect of opioid-free anesthesia on the quality of recovery, using lidocaine on patients undergoing hysteroscopy. Methods A parallel-group, randomized, double-blind, controlled trial was conducted in Yichang Central Peoples’ Hospital, Hubei Province, China, from January to April, 2022. We included 90 female patients (age: 18–65 years, American Society of Anesthesiologists Physical Status Class I–II) scheduled for elective hysteroscopy, 45 of whom received lidocaine (Group L), and 45 received sufentanil (Group S). Patients were randomly allocated to receive either lidocaine or sufentanil perioperatively. The primary outcome was the quality of postoperative recovery, which was assessed using the QoR-40 questionnaire (a patient-reported outcome questionnaire measuring the quality of recovery after surgery). Results The two groups were similar in age, American Society of Anesthesiology physical status, height, weight, body mass index, and surgical duration. The QoR scores were significantly higher in Group L than Group S. The incidence of postoperative nausea and vomiting, as well as the time to extubation were significantly lower in Group L than Group S. Conclusion Opioid-free anesthesia with lidocaine achieves a better quality of recovery, faster recovery, and a shorter time to extubation than general anesthesia with sufentanil. Trial registration The trial was registered on January 15, 2022 in the Chinese Clinical Trial Registry ( http://www.chictr.org.cn/showprojen.aspx?proj=149386 ), registration number ChiCTR2200055623.(15/01/2022). |
| first_indexed | 2024-03-13T07:21:44Z |
| format | Article |
| id | doaj.art-efe34713cf334501b2aed1ea51a54af7 |
| institution | Directory Open Access Journal |
| issn | 1471-2253 |
| language | English |
| last_indexed | 2024-03-13T07:21:44Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Anesthesiology |
| spelling | doaj.art-efe34713cf334501b2aed1ea51a54af72023-06-04T11:37:07ZengBMCBMC Anesthesiology1471-22532023-06-012311510.1186/s12871-023-02152-7Opioid-free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy: a randomized controlled trialNH Cha0Y Hu1GH Zhu2X Long3JJ Jiang4Yuan Gong5Institute of Anesthesiology and Critical Care Medicine, Three Gorges University & Yichang Central People’s HospitalInstitute of Anesthesiology and Critical Care Medicine, Three Gorges University & Yichang Central People’s HospitalInstitute of Anesthesiology and Critical Care Medicine, Three Gorges University & Yichang Central People’s HospitalInstitute of Anesthesiology and Critical Care Medicine, Three Gorges University & Yichang Central People’s HospitalInstitute of Anesthesiology and Critical Care Medicine, Three Gorges University & Yichang Central People’s HospitalInstitute of Anesthesiology and Critical Care Medicine, Three Gorges University & Yichang Central People’s HospitalAbstract Background Anesthesia with opioids negatively affects patients’ quality of recovery. Opioid-free anesthesia attempts to avoid these effects. This study aimed to evaluate the effect of opioid-free anesthesia on the quality of recovery, using lidocaine on patients undergoing hysteroscopy. Methods A parallel-group, randomized, double-blind, controlled trial was conducted in Yichang Central Peoples’ Hospital, Hubei Province, China, from January to April, 2022. We included 90 female patients (age: 18–65 years, American Society of Anesthesiologists Physical Status Class I–II) scheduled for elective hysteroscopy, 45 of whom received lidocaine (Group L), and 45 received sufentanil (Group S). Patients were randomly allocated to receive either lidocaine or sufentanil perioperatively. The primary outcome was the quality of postoperative recovery, which was assessed using the QoR-40 questionnaire (a patient-reported outcome questionnaire measuring the quality of recovery after surgery). Results The two groups were similar in age, American Society of Anesthesiology physical status, height, weight, body mass index, and surgical duration. The QoR scores were significantly higher in Group L than Group S. The incidence of postoperative nausea and vomiting, as well as the time to extubation were significantly lower in Group L than Group S. Conclusion Opioid-free anesthesia with lidocaine achieves a better quality of recovery, faster recovery, and a shorter time to extubation than general anesthesia with sufentanil. Trial registration The trial was registered on January 15, 2022 in the Chinese Clinical Trial Registry ( http://www.chictr.org.cn/showprojen.aspx?proj=149386 ), registration number ChiCTR2200055623.(15/01/2022).https://doi.org/10.1186/s12871-023-02152-7Opioid-free anesthesiaOpioidsPostoperative nausea and vomitingQuality of recovery (QoR) |
| spellingShingle | NH Cha Y Hu GH Zhu X Long JJ Jiang Yuan Gong Opioid-free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy: a randomized controlled trial BMC Anesthesiology Opioid-free anesthesia Opioids Postoperative nausea and vomiting Quality of recovery (QoR) |
| title | Opioid-free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy: a randomized controlled trial |
| title_full | Opioid-free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy: a randomized controlled trial |
| title_fullStr | Opioid-free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy: a randomized controlled trial |
| title_full_unstemmed | Opioid-free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy: a randomized controlled trial |
| title_short | Opioid-free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy: a randomized controlled trial |
| title_sort | opioid free anesthesia with lidocaine for improved postoperative recovery in hysteroscopy a randomized controlled trial |
| topic | Opioid-free anesthesia Opioids Postoperative nausea and vomiting Quality of recovery (QoR) |
| url | https://doi.org/10.1186/s12871-023-02152-7 |
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