Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management
Atrial fibrillation (AF) is a common complication of the early postoperative period of various types of surgery, including that for lung cancer. Although induced by the homeostatic alterations related to surgery, there is evidence that it is not a mere stand-alone transitory event, but it represents...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/13/16/4012 |
| _version_ | 1797524479163760640 |
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| author | Gennaro Carmine Semeraro Carlo Ambrogio Meroni Carlo Maria Cipolla Daniela Maria Cardinale |
| author_facet | Gennaro Carmine Semeraro Carlo Ambrogio Meroni Carlo Maria Cipolla Daniela Maria Cardinale |
| author_sort | Gennaro Carmine Semeraro |
| collection | DOAJ |
| description | Atrial fibrillation (AF) is a common complication of the early postoperative period of various types of surgery, including that for lung cancer. Although induced by the homeostatic alterations related to surgery, there is evidence that it is not a mere stand-alone transitory event, but it represents a relevant complication of surgery, bearing considerable prognostic consequences. Different methods have therefore been explored to predict the occurrence of postoperative atrial fibrillation (POAF) and prevent it. In particular, the age among clinical factors, and N-terminal prohormone of brain natriuretic peptide (NT-proBNP), as a marker, have proven to be good predictors, and the use of beta-blockers or amiodarone in primary prevention seems to reduce its incidence significantly. There is growing evidence that POAF significantly increases the risk of stroke and global mortality in the long term; therefore, it should be managed in the same way as spontaneous atrial fibrillation. In this review, we will present the strongest evidence found so far and the most recent findings regarding the management of POAF, with a special focus on patients undergoing thoracic surgery for lung cancer. |
| first_indexed | 2024-03-10T08:57:59Z |
| format | Article |
| id | doaj.art-efe70853c3b34f8c923b39ff5da5b27f |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T08:57:59Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-efe70853c3b34f8c923b39ff5da5b27f2023-11-22T07:02:27ZengMDPI AGCancers2072-66942021-08-011316401210.3390/cancers13164012Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation ManagementGennaro Carmine Semeraro0Carlo Ambrogio Meroni1Carlo Maria Cipolla2Daniela Maria Cardinale3Cardioncology Unit, European Institute of Oncology, IRCCS, 20145 Milan, MI, ItalyCardiology Department, European Institute of Oncology, IRCCS, 20145 Milan, MI, ItalyCardiology Department, European Institute of Oncology, IRCCS, 20145 Milan, MI, ItalyCardioncology Unit, European Institute of Oncology, IRCCS, 20145 Milan, MI, ItalyAtrial fibrillation (AF) is a common complication of the early postoperative period of various types of surgery, including that for lung cancer. Although induced by the homeostatic alterations related to surgery, there is evidence that it is not a mere stand-alone transitory event, but it represents a relevant complication of surgery, bearing considerable prognostic consequences. Different methods have therefore been explored to predict the occurrence of postoperative atrial fibrillation (POAF) and prevent it. In particular, the age among clinical factors, and N-terminal prohormone of brain natriuretic peptide (NT-proBNP), as a marker, have proven to be good predictors, and the use of beta-blockers or amiodarone in primary prevention seems to reduce its incidence significantly. There is growing evidence that POAF significantly increases the risk of stroke and global mortality in the long term; therefore, it should be managed in the same way as spontaneous atrial fibrillation. In this review, we will present the strongest evidence found so far and the most recent findings regarding the management of POAF, with a special focus on patients undergoing thoracic surgery for lung cancer.https://www.mdpi.com/2072-6694/13/16/4012anticoagulationamiodaronebeta-blockerslung cancerNT-proBNPpostoperative atrial fibrillation |
| spellingShingle | Gennaro Carmine Semeraro Carlo Ambrogio Meroni Carlo Maria Cipolla Daniela Maria Cardinale Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management Cancers anticoagulation amiodarone beta-blockers lung cancer NT-proBNP postoperative atrial fibrillation |
| title | Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management |
| title_full | Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management |
| title_fullStr | Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management |
| title_full_unstemmed | Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management |
| title_short | Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management |
| title_sort | atrial fibrillation after lung cancer surgery prediction prevention and anticoagulation management |
| topic | anticoagulation amiodarone beta-blockers lung cancer NT-proBNP postoperative atrial fibrillation |
| url | https://www.mdpi.com/2072-6694/13/16/4012 |
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