Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report
Abstract Background Cardiac metastases in hepatocellular carcinoma patients are infrequently encountered and usually associated with a very poor prognosis. Case presentation Hereby, we report a case of an acute pulmonary embolism (PE) on top of HCC with direct cardiac invasion to the right atrium (R...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2021-07-01
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| Series: | The Egyptian Heart Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43044-021-00193-2 |
| _version_ | 1818354008759205888 |
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| author | Mahmoud Abdelnabi Yehia Saleh Abdallah Almaghraby Özge Özden Tok Hoda Abdelgawad Sherif Abd ElSamad |
| author_facet | Mahmoud Abdelnabi Yehia Saleh Abdallah Almaghraby Özge Özden Tok Hoda Abdelgawad Sherif Abd ElSamad |
| author_sort | Mahmoud Abdelnabi |
| collection | DOAJ |
| description | Abstract Background Cardiac metastases in hepatocellular carcinoma patients are infrequently encountered and usually associated with a very poor prognosis. Case presentation Hereby, we report a case of an acute pulmonary embolism (PE) on top of HCC with direct cardiac invasion to the right atrium (RA) through the inferior vena cava with another metastasis to the right ventricular apex in the form of highly mobile cauliflower mass protruding through the tricuspid valve into RA and nearly obliterating right ventricular outflow tract in a multi-centric hepatocellular carcinoma patient. Conclusion Acute dyspnea in a patient with a long history of hepatitis C virus infection raises the suspicion of acute PE due to either hypercoagulable state induced by malignancy or by cardiac extension of the tumor which usually carries high mortality rates. To the best of our knowledge, this case is the first case in the literature to show cardiac metastases in HCC with two different pathological mechanisms. |
| first_indexed | 2024-12-13T19:18:36Z |
| format | Article |
| id | doaj.art-efe9b1bddb334b01957d4f9a5f0b02f1 |
| institution | Directory Open Access Journal |
| issn | 2090-911X |
| language | English |
| last_indexed | 2024-12-13T19:18:36Z |
| publishDate | 2021-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Heart Journal |
| spelling | doaj.art-efe9b1bddb334b01957d4f9a5f0b02f12022-12-21T23:34:14ZengSpringerOpenThe Egyptian Heart Journal2090-911X2021-07-017311310.1186/s43044-021-00193-2Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case reportMahmoud Abdelnabi0Yehia Saleh1Abdallah Almaghraby2Özge Özden Tok3Hoda Abdelgawad4Sherif Abd ElSamad5Cardiology and Angiology Unit, Department of Clinical and Experimental Internal Medicine, Medical Research Institute, Alexandria UniversityCardiology Department, Houston Methodist HospitalCardiology Department, Faculty of Medicine, University of AlexandriaCardiology Department, Memorial Bahçelievler HospitalCardiology Department, Houston Methodist HospitalCardiology and Angiology Unit, Department of Clinical and Experimental Internal Medicine, Medical Research Institute, Alexandria UniversityAbstract Background Cardiac metastases in hepatocellular carcinoma patients are infrequently encountered and usually associated with a very poor prognosis. Case presentation Hereby, we report a case of an acute pulmonary embolism (PE) on top of HCC with direct cardiac invasion to the right atrium (RA) through the inferior vena cava with another metastasis to the right ventricular apex in the form of highly mobile cauliflower mass protruding through the tricuspid valve into RA and nearly obliterating right ventricular outflow tract in a multi-centric hepatocellular carcinoma patient. Conclusion Acute dyspnea in a patient with a long history of hepatitis C virus infection raises the suspicion of acute PE due to either hypercoagulable state induced by malignancy or by cardiac extension of the tumor which usually carries high mortality rates. To the best of our knowledge, this case is the first case in the literature to show cardiac metastases in HCC with two different pathological mechanisms.https://doi.org/10.1186/s43044-021-00193-2Hepatitis C virusPulmonary embolismHepatocellular carcinomaEchocardiography |
| spellingShingle | Mahmoud Abdelnabi Yehia Saleh Abdallah Almaghraby Özge Özden Tok Hoda Abdelgawad Sherif Abd ElSamad Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report The Egyptian Heart Journal Hepatitis C virus Pulmonary embolism Hepatocellular carcinoma Echocardiography |
| title | Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report |
| title_full | Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report |
| title_fullStr | Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report |
| title_full_unstemmed | Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report |
| title_short | Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report |
| title_sort | acute pulmonary embolism in a patient with hepatitis c virus infection and hepatocellular carcinoma a case report |
| topic | Hepatitis C virus Pulmonary embolism Hepatocellular carcinoma Echocardiography |
| url | https://doi.org/10.1186/s43044-021-00193-2 |
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