Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge <i>Crambe tailliezi</i>

Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge <i>Crambe tailliezi</i>

Regulated cell death (RCD) results from the activation of one or more signal transduction modules both in physiological or pathological conditions. It is now established that RCD is involved in numerous human diseases, including cancer. As regulated cell death processes can be modulated by pharmacol...

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Bibliographic Details
Main Authors: Thi-Ngoc-Dung Nguyen, Omid Feizbakhsh, Estelle Sfecci, Blandine Baratte, Claire Delehouzé, Adrien Garcia, Corentin Moulin, Pierre Colas, Sandrine Ruchaud, Mohamed Mehiri, Stéphane Bach
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Marine Drugs
Subjects:
screening
kinase inhibition
regulated cell death
rip1-independent cell death
marine natural products
<i>crambe tailliezi</i>
Online Access:https://www.mdpi.com/1660-3397/17/10/569

Internet

https://www.mdpi.com/1660-3397/17/10/569

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