Optic nerve and vitreal inflammation are both RGC neuroprotective but only the latter is RGC axogenic

Optic nerve and vitreal inflammation are both RGC neuroprotective but only the latter is RGC axogenic

Intravitreal inflammation, induced by either lens injury, or intravitreal injection of zymosan (IVZ), protects RGC from apoptosis and stimulates axon regeneration after optic nerve transection. Here, we investigate the differential effects of intra-optic nerve zymosan (ONZ) and IVZ injections on RGC...

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Bibliographic Details
Main Authors: Zubair Ahmed, Mudasser Aslam, Barbara Lorber, Ellen L. Suggate, Martin Berry, Ann Logan
Format: Article
Language:English
Published: Elsevier 2010-02-01
Series:Neurobiology of Disease
Subjects:
Macrophages
RGC survival/axon regeneration
Müller cells
Astrocytes
Neurite outgrowth
Zymosan
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109003106

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