Output-Specific Adaptation of Habenula-Midbrain Excitatory Synapses During Cocaine Withdrawal

Output-Specific Adaptation of Habenula-Midbrain Excitatory Synapses During Cocaine Withdrawal

Projections from the lateral habenula (LHb) control ventral tegmental area (VTA) neuronal populations’ activity and both nuclei shape the pathological behaviors emerging during cocaine withdrawal. However, it is unknown whether cocaine withdrawal modulates LHb neurotransmission onto subsets of VTA n...

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Bibliographic Details
Main Authors: Joseph Clerke, Patricia Preston-Ferrer, Ioannis S. Zouridis, Audrey Tissot, Laura Batti, Fabian F. Voigt, Stephane Pagès, Andrea Burgalossi, Manuel Mameli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
ventral tegmental area
lateral habenula
cocaine
synaptic plasticity
glutamatergic transmission
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.643138/full

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