EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children

EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children

The EuroFlow PID consortium developed a set of flow cytometry tests for evaluation of patients with suspicion of primary immunodeficiency (PID). In this technical report we evaluate the performance of the SCID-RTE tube that explores the presence of recent thymic emigrants (RTE) together with T-cell...

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Main Authors: Tomas Kalina, Marina Bakardjieva, Maartje Blom, Martin Perez-Andres, Barbara Barendregt, Veronika Kanderová, Carolien Bonroy, Jan Philippé, Elena Blanco, Ingrid Pico-Knijnenburg, Jitse H. M. P. Paping, Beata Wolska-Kuśnierz, Malgorzata Pac, Jakub Tkazcyk, Filomeen Haerynck, Himmet Haluk Akar, Renata Formánková, Tomáš Freiberger, Michael Svatoň, Anna Šedivá, Sonia Arriba-Méndez, Alberto Orfao, Jacques J. M. van Dongen, Mirjam van der Burg
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
flow cytometric immunophenotyping
primary immunodeficiencies (PID)
EuroFlow
standardization
severe combined immune deficiency (SCID)
diagnosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00371/full

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