A scoping review on the significance of programmed death-ligand 1-inhibiting microRNAs in non-small cell lung treatment: A single-cell RNA sequencing-based study

BackgroundThe programmed death-ligand 1 (PD-L1)/PD-1 axis is one of the well-established inhibitory axes in regulating immune responses. Besides the significance of tumor-intrinsic PD-L1 expression in immune evasion, its oncogenic role has been implicated in various malignancies, like non-small cell...

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Main Authors: Mahdi Abdoli Shadbad, Farid Ghorbaninezhad, Hamidreza Hassanian, Noora Karim Ahangar, Negar Hosseinkhani, Afshin Derakhshani, Najibeh Shekari, Oronzo Brunetti, Nicola Silvestris, Behzad Baradaran
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1027758/full