Four hepatosplenic T-cell lymphoma cases of Japanese patients
Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an eld...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-01-01
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| Series: | Leukemia Research Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213048915300200 |
| _version_ | 1818876972427640832 |
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| author | Hidetsugu Kawai Hiromichi Matsushita Ken Ohmachi Minoru Kojima Shinichiro Machida Yoshiaki Ogawa Hiroshi Kawada Naoya Nakamura Kiyoshi Ando |
| author_facet | Hidetsugu Kawai Hiromichi Matsushita Ken Ohmachi Minoru Kojima Shinichiro Machida Yoshiaki Ogawa Hiroshi Kawada Naoya Nakamura Kiyoshi Ando |
| author_sort | Hidetsugu Kawai |
| collection | DOAJ |
| description | Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age. |
| first_indexed | 2024-12-19T13:50:53Z |
| format | Article |
| id | doaj.art-efede19e8a3848818bebe9cbfb4cca75 |
| institution | Directory Open Access Journal |
| issn | 2213-0489 |
| language | English |
| last_indexed | 2024-12-19T13:50:53Z |
| publishDate | 2016-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Leukemia Research Reports |
| spelling | doaj.art-efede19e8a3848818bebe9cbfb4cca752022-12-21T20:18:45ZengElsevierLeukemia Research Reports2213-04892016-01-015C3610.1016/j.lrr.2015.12.001Four hepatosplenic T-cell lymphoma cases of Japanese patientsHidetsugu Kawai0Hiromichi Matsushita1Ken Ohmachi2Minoru Kojima3Shinichiro Machida4Yoshiaki Ogawa5Hiroshi Kawada6Naoya Nakamura7Kiyoshi Ando8Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanHepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.http://www.sciencedirect.com/science/article/pii/S2213048915300200Hepatosplenic T-cell lymphomaImmunodeficiencyElderly patients |
| spellingShingle | Hidetsugu Kawai Hiromichi Matsushita Ken Ohmachi Minoru Kojima Shinichiro Machida Yoshiaki Ogawa Hiroshi Kawada Naoya Nakamura Kiyoshi Ando Four hepatosplenic T-cell lymphoma cases of Japanese patients Leukemia Research Reports Hepatosplenic T-cell lymphoma Immunodeficiency Elderly patients |
| title | Four hepatosplenic T-cell lymphoma cases of Japanese patients |
| title_full | Four hepatosplenic T-cell lymphoma cases of Japanese patients |
| title_fullStr | Four hepatosplenic T-cell lymphoma cases of Japanese patients |
| title_full_unstemmed | Four hepatosplenic T-cell lymphoma cases of Japanese patients |
| title_short | Four hepatosplenic T-cell lymphoma cases of Japanese patients |
| title_sort | four hepatosplenic t cell lymphoma cases of japanese patients |
| topic | Hepatosplenic T-cell lymphoma Immunodeficiency Elderly patients |
| url | http://www.sciencedirect.com/science/article/pii/S2213048915300200 |
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