Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment
Abstract Aim Although studies in Western countries have investigated the quality of life (QoL) of heroin users, limited research on this topic has been conducted in Asia. The present study assessed QoL in patients with heroin dependence receiving medications to treat opioid use disorder. Methods We...
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| Format: | Article |
| Language: | English |
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Wiley
2023-12-01
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| Series: | Neuropsychopharmacology Reports |
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| Online Access: | https://doi.org/10.1002/npr2.12402 |
| _version_ | 1797382747439759360 |
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| author | Hu‐Ming Chang Ming‐Chyi Huang Su‐Chen Fang Shih‐Ku Lin |
| author_facet | Hu‐Ming Chang Ming‐Chyi Huang Su‐Chen Fang Shih‐Ku Lin |
| author_sort | Hu‐Ming Chang |
| collection | DOAJ |
| description | Abstract Aim Although studies in Western countries have investigated the quality of life (QoL) of heroin users, limited research on this topic has been conducted in Asia. The present study assessed QoL in patients with heroin dependence receiving medications to treat opioid use disorder. Methods We performed a cross‐sectional study of patients with heroin dependence receiving methadone and buprenorphine treatment. The demographic and substance use variables of patients receiving methadone and buprenorphine were compared. The Chinese Health Questionnaire (CHQ‐12), Obsessive Compulsive Drug Use Scale (OCDUS), and World Health Organization Quality of Life Short Form Taiwan version (WHOQOL‐BREF‐T) were administered to measure patient mental health problems, addiction severity, and QoL, respectively. Multivariate regression was used to identify the factors associated with QoL. Results A total of 149 patients receiving methadone and 31 receiving buprenorphine completed the questionnaires. Individuals in the buprenorphine group were more likely to be married (p = 0.024) or employed (p = 0.024), have a higher educational level (p = 0.013), have lower drug craving (OCDUS: p = 0.035), or have higher QoL (WHOQOL‐BREF‐T: p = 0.004) than those in the methadone group. After adjustment for other variables, employment was positively associated with the physical, psychological, and environmental domains of QoL. Receiving buprenorphine treatment (p = 0.032) and longer treatment duration (p = 0.016) were associated with higher psychological QoL. Conclusion Several factors were associated with QoL in patients with heroin dependence. Some measures may improve their QoL, such as reducing employment barriers, improving treatment adherence, or increasing accessibility to buprenorphine treatment. |
| first_indexed | 2024-03-08T21:10:55Z |
| format | Article |
| id | doaj.art-efeee75c358c4000b39470123a6848ae |
| institution | Directory Open Access Journal |
| issn | 2574-173X |
| language | English |
| last_indexed | 2024-03-08T21:10:55Z |
| publishDate | 2023-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neuropsychopharmacology Reports |
| spelling | doaj.art-efeee75c358c4000b39470123a6848ae2023-12-22T07:25:34ZengWileyNeuropsychopharmacology Reports2574-173X2023-12-0143460761510.1002/npr2.12402Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatmentHu‐Ming Chang0Ming‐Chyi Huang1Su‐Chen Fang2Shih‐Ku Lin3Department of Addiction Sciences, Taipei City Psychiatric Center Taipei City Hospital Taipei TaiwanDepartment of Addiction Sciences, Taipei City Psychiatric Center Taipei City Hospital Taipei TaiwanDepartment of Nursing Mackay Medical College Taipei TaiwanSchool of Medicine, College of Medicine Taipei Medical University Taipei TaiwanAbstract Aim Although studies in Western countries have investigated the quality of life (QoL) of heroin users, limited research on this topic has been conducted in Asia. The present study assessed QoL in patients with heroin dependence receiving medications to treat opioid use disorder. Methods We performed a cross‐sectional study of patients with heroin dependence receiving methadone and buprenorphine treatment. The demographic and substance use variables of patients receiving methadone and buprenorphine were compared. The Chinese Health Questionnaire (CHQ‐12), Obsessive Compulsive Drug Use Scale (OCDUS), and World Health Organization Quality of Life Short Form Taiwan version (WHOQOL‐BREF‐T) were administered to measure patient mental health problems, addiction severity, and QoL, respectively. Multivariate regression was used to identify the factors associated with QoL. Results A total of 149 patients receiving methadone and 31 receiving buprenorphine completed the questionnaires. Individuals in the buprenorphine group were more likely to be married (p = 0.024) or employed (p = 0.024), have a higher educational level (p = 0.013), have lower drug craving (OCDUS: p = 0.035), or have higher QoL (WHOQOL‐BREF‐T: p = 0.004) than those in the methadone group. After adjustment for other variables, employment was positively associated with the physical, psychological, and environmental domains of QoL. Receiving buprenorphine treatment (p = 0.032) and longer treatment duration (p = 0.016) were associated with higher psychological QoL. Conclusion Several factors were associated with QoL in patients with heroin dependence. Some measures may improve their QoL, such as reducing employment barriers, improving treatment adherence, or increasing accessibility to buprenorphine treatment.https://doi.org/10.1002/npr2.12402buprenorphineheroin dependencemedications to treat opioid use disordermethadonequality of life |
| spellingShingle | Hu‐Ming Chang Ming‐Chyi Huang Su‐Chen Fang Shih‐Ku Lin Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment Neuropsychopharmacology Reports buprenorphine heroin dependence medications to treat opioid use disorder methadone quality of life |
| title | Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment |
| title_full | Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment |
| title_fullStr | Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment |
| title_full_unstemmed | Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment |
| title_short | Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment |
| title_sort | quality of life and associated factors of heroin dependent patients receiving methadone and buprenorphine maintenance treatment |
| topic | buprenorphine heroin dependence medications to treat opioid use disorder methadone quality of life |
| url | https://doi.org/10.1002/npr2.12402 |
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