ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking in Ciona notochord
Lumen development is a crucial phase in tubulogenesis, although its molecular mechanisms are largely unknown. In this study, we discovered an ELMO domain-containing 3 (ELMOD3), which belongs to ADP-ribosylation factor GTPase-activating protein family, was necessary to form the notochord lumen in Cio...
Main Authors: | Amei Liu, Xiuke Ouyang, Zhuqing Wang, Bo Dong |
---|---|
Format: | Article |
Language: | English |
Published: |
The Royal Society
2023-03-01
|
Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.220367 |
Similar Items
-
Quantitative Phosphoproteomics Reveals the Requirement of DYRK1-Mediated Phosphorylation of Ion Transport- and Cell Junction-Related Proteins for Notochord Lumenogenesis in Ascidian
by: Zhuqing Wang, et al.
Published: (2023-03-01) -
MiR-92 Family Members Form a Cluster Required for Notochord Tubulogenesis in Urochordate <i>Ciona savignyi</i>
by: Libo Yang, et al.
Published: (2021-03-01) -
Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27
by: Camille Menaceur, et al.
Published: (2023-12-01) -
Members of the ELMOD protein family specify formation of distinct aperture domains on the Arabidopsis pollen surface
by: Yuan Zhou, et al.
Published: (2021-09-01) -
Immunohistochemical study of cytoskeletal and extracellular matrix components in the notochord and notochordal sheath of amphioxus
Published: (2006-04-01)