Schip1 is a novel podocyte foot process protein that mediates actin cytoskeleton rearrangements and forms a complex with Nherf2 and ezrin.

Podocyte foot process effacement accompanied by actin cytoskeleton rearrangements is a cardinal feature of many progressive human proteinuric diseases.By microarray profiling of mouse glomerulus, SCHIP1 emerged as one of the most highly enriched transcripts. We detected Schip1 protein in the kidney...

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Main Authors: Ljubica Perisic, Patricia Q Rodriguez, Kjell Hultenby, Ying Sun, Mark Lal, Christer Betsholtz, Mathias Uhlén, Annika Wernerson, Ulf Hedin, Timo Pikkarainen, Karl Tryggvason, Jaakko Patrakka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4373682?pdf=render

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