472 Utility of [89Zr]Trastuzumab-PET/MRI Imaging for Quantitative Assessment of Tumor Heterogeneity In HER2+ Breast Cancer

472 Utility of [89Zr]Trastuzumab-PET/MRI Imaging for Quantitative Assessment of Tumor Heterogeneity In HER2+ Breast Cancer

OBJECTIVES/GOALS: This study was performed to explore the capabilities of simultaneous [89 Zr]trastuzumab-PET/MRI acquisition in a cohort of metastatic HER2+ breast cancer. The insights derived provide additional noninvasive characterization and precise intratumoral analysis tools for healthcare pro...

Full description

Bibliographic Details
Main Authors:	Ameer Mansur, Moozhan Nikpanah, Johnathan McConathy, Erica Stringer-Reasor, Gabrielle Rocque, Ahmed Elkhanany, Katia Khoury, Nusrat Jahan, Suzanne E. Lapi, Anna G. Sorace
Format:	Article
Language:	English
Published:	Cambridge University Press 2024-04-01
Series:	Journal of Clinical and Translational Science
Online Access:	https://www.cambridge.org/core/product/identifier/S205986612400400X/type/journal_article

Similar Items

Modulation of the Tumor Microenvironment with Trastuzumab Enables Radiosensitization in HER2+ Breast Cancer
by: Patrick N. Song, et al.
Published: (2022-02-01)

Combination Therapy with Trastuzumab and Niraparib: Quantifying Early Proliferative Alterations in HER2+ Breast Cancer Models
by: Ameer Mansur, et al.
Published: (2023-07-01)

[<sup>89</sup>Zr]-Atezolizumab-PET Imaging Reveals Longitudinal Alterations in PDL1 during Therapy in TNBC Preclinical Models
by: Adriana V. F. Massicano, et al.
Published: (2023-05-01)

Development and evaluation of 89Zr-trastuzumab for clinical applications
by: Fatemeh Mohammadpour-Ghazi, et al.
Published: (2023-06-01)

[<sup>89</sup>Zr]-Pertuzumab PET Imaging Reveals Paclitaxel Treatment Efficacy Is Positively Correlated with HER2 Expression in Human Breast Cancer Xenograft Mouse Models
by: Yun Lu, et al.
Published: (2021-03-01)

Therapeutic Response Monitoring with <sup>89</sup>Zr-DFO-Pertuzumab in HER2-Positive and Trastuzumab-Resistant Breast Cancer Models
by: Minwoo Kang, et al.
Published: (2022-06-01)

Synthesis and Feasibility Evaluation of a new Trastuzumab Conjugate Integrated with Paclitaxel and 89Zr for Theranostic Application Against HER2‐Expressing Breast Cancers
by: Dr. Joo Hee Jang, et al.
Published: (2019-04-01)

EMG 472 - PEMBUATAN LANJUTAN APRIL 1993.
by: PPKM, Pusat Pengajian Kejuruteraan Mekanikal
Published: (1993)

EMG 472 - PEMBUATAN LANJUTAN JUN 1994.
by: PPKM, Pusat Pengajian Kejuruteraan Mekanikal
Published: (1994)

In-Trastuzumab Scintigraphy in HER2-Positive Metastatic Breast Cancer Patients Remains Feasible during Trastuzumab Treatment
by: Sietske B.M. Gaykema, et al.
Published: (2014-07-01)

Neratinib plus trastuzumab is superior to pertuzumab plus trastuzumab in HER2-positive breast cancer xenograft models
by: Jamunarani Veeraraghavan, et al.
Published: (2021-05-01)

Termination of trastuzumab in HER2-positive metastatic breast cancer patients who received trastuzumab beyond progression
by: Izzet Dogan, et al.
Published: (2023-05-01)

EEK 472 – ANALISA SISTEM KUASA JANUARI 2012
by: PPKEE, Pusat Pengajian Kejuruteraan Elektrik & Elektronik
Published: (2012)

ACW 472 - MANAGEMENT ACCOUNTING AND CONTROL APRIL 08.
by: PPP, Pusat Pengajian Pengurusan
Published: (2008)

BOO 472-2 - EVOLUSI OKT.1987-88.
by: PPSKJ, Pusat Pengajian Sains Kajihayat
Published: (1988)

BOO 472-2 - EVOLUSI OKT- NOV. 1989
by: PPSKJ, Pusat Pengajian Sains Kajihayat
Published: (1989)

EEK472 – POWER SYSTEM ANALYSIS JANUARY 2013
by: PPKEE, Pusat Pengajian Kejuruteraan Elektrik & Elektronik
Published: (2013)

EEK472 – POWER SYSTEM ANALYSIS JANUARY 2014
by: PPKEE, Pusat Pengajian Kejuruteraan Elektrik & Elektronik
Published: (2014)

EEE 472 - SISTEM PERHUBUNGAN LANJUTAN FEB 1998
by: PPKEE, Pusat Pengajian Kejuruteraan Elektrik & Elektronik
Published: (1998)

3,472 UMP students receive student devices
by: Mimi Rabita, Abdul Wahit
Published: (2022)

3,472 mahasiswa UMP terima peranti siswa
by: Mimi Rabita, Abdul Wahit
Published: (2022)

Quantification of Trastuzumab–HER2 Engagement In Vitro and In Vivo
by: Alena Rudkouskaya, et al.
Published: (2020-12-01)

Resistance to Trastuzumab
by: Sneha Vivekanandhan, et al.
Published: (2022-10-01)

Exploring the Combined Action of Adding Pertuzumab to Branded Trastuzumab versus Trastuzumab Biosimilars for Treating HER2+ Breast Cancer
by: Emma Franco-Mateos, et al.
Published: (2024-04-01)

Aggressive HER2-Positive Gastric Cancer in a Young Patient, Refractory in Trastuzumab and Progressive with Trastuzumab-Emtansine Treatment
by: Vildana Goga Çmega, et al.
Published: (2024-03-01)

Comparing pyrotinib with trastuzumab and pertuzumab with trastuzumab for HER2-positive metastatic breast cancer: a retrospective, multicenter analysis
by: Shuhui You, et al.
Published: (2023-12-01)

Takotsubo Syndrome during Pertuzumab and Trastuzumab Therapy for HER2-Positive Metastatic Breast Cancer
by: Azzurra Irelli, et al.
Published: (2024-01-01)

<sup>89</sup>Zr-Trastuzumab PET/CT Imaging of HER2-Positive Breast Cancer for Predicting Pathological Complete Response after Neoadjuvant Systemic Therapy: A Feasibility Study
by: D. G. J. Linders, et al.
Published: (2023-10-01)

In era of immunotherapy: the value of trastuzumab beyond progression in patients with trastuzumab-resistant HER2-positive advanced or metastatic gastric cancer
by: Hui Wang, et al.
Published: (2024-04-01)

Quantifying the Effects of Combination Trastuzumab and Radiation Therapy in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer
by: Meghan J. Bloom, et al.
Published: (2022-08-01)

EKC 472 - KEJURUTERAAN KAWALAN PENCEMARAN AIR OKT 04.
by: PPKK, Pusat Pengajian Kejuruteraan Kimia
Published: (2004)

BTI 472-2 - KEJURUTERAAN BIOKIMIA MAC-APRIL 1989.
by: PPSKJ, Pusat Pengajian Sains Kajihayat
Published: (1989)

ZGE 472/3 - PEMPROSESAN DATA SEISMIK APRIL 1997.
by: PPSF, Pusat Pengajian Sains Fizik
Published: (1997)

ZGE 472/3 Pemprosesan Data Seismik April 1995
by: PPSF, Pusat Pengajian Sains Fizik
Published: (1995)

ZGE 472/3 - PEMPROSESAN DATA SEISMIK APRIL 1995.
by: PPSF, Pusat Pengajian Sains Fizik
Published: (1995)

ZGE 472-3 - PEMPROSESAN DATA SEISMIK APR 1994
by: PPSF, Pusat Pengajian Sains Fizik
Published: (1994)

EKC 472- KEJURUTERAAN KAWALAN PENCEMARAN AIR NOV 05.
by: PPKK, Pusat Pengajian Kejuruteraan Kimia
Published: (2005)

Effects of trastuzumab and trastuzumab emtansine on corrected QT interval and left ventricular ejection fraction in patients with metastatic (HER2+) breast cancer
by: Rea Levicki, et al.
Published: (2023-02-01)

Image Quantification for TSPO PET with a Novel Image-Derived Input Function Method
by: Yu-Hua Dean Fang, et al.
Published: (2022-05-01)

YES1 as a Therapeutic Target for HER2-Positive Breast Cancer after Trastuzumab and Trastuzumab-Emtansine (T-DM1) Resistance Development
by: Miwa Fujihara, et al.
Published: (2021-11-01)