Transvaginal Ultrasound Accuracy in the Hydrosalpinx Diagnosis: A Systematic Review and Meta-Analysis
Hydrosalpinx is a condition with a crucial prognostic role in reproduction, and its diagnosis by a non-invasive technique such as ultrasound is key in achieving an adequate reproductive assessment while avoiding unnecessary laparoscopies. The aim of the present systematic review and meta-analysis is...
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MDPI AG
2023-03-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/5/948 |
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| author | Aina Delgado-Morell Mar Nieto-Tous Cristina Andrada-Ripollés Maria Ángela Pascual Silvia Ajossa Stefano Guerriero Juan Luis Alcázar |
| author_facet | Aina Delgado-Morell Mar Nieto-Tous Cristina Andrada-Ripollés Maria Ángela Pascual Silvia Ajossa Stefano Guerriero Juan Luis Alcázar |
| author_sort | Aina Delgado-Morell |
| collection | DOAJ |
| description | Hydrosalpinx is a condition with a crucial prognostic role in reproduction, and its diagnosis by a non-invasive technique such as ultrasound is key in achieving an adequate reproductive assessment while avoiding unnecessary laparoscopies. The aim of the present systematic review and meta-analysis is to synthetize and report the current evidence on transvaginal sonography (TVS) accuracy to diagnose hydrosalpinx. Articles on the topic published between January 1990 and December 2022 were searched in five electronic databases. Data from the six selected studies, comprising 4144 adnexal masses in 3974 women, 118 of which were hydrosalpinxes, were analyzed as follows: overall, TVS had a pooled estimated sensitivity for hydrosalpinx of 84% (95% confidence interval (CI) = 76–89%), specificity of 99% (95% CI = 98–100%), positive likelihood ratio of 80.7 (95% CI = 33.7–193.0), and negative likelihood ratio of 0.16 (95% CI = 0.11–0.25) and DOR of 496 (95% CI = 178–1381). The mean prevalence of hydrosalpinx was 4%. The quality of the studies and their risk of bias were assessed using QUADAS-2, evidencing an overall acceptable quality of the selected articles. We concluded that TVS has a good specificity and sensitivity for diagnosing hydrosalpinx. |
| first_indexed | 2024-03-11T07:28:11Z |
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| id | doaj.art-effc4e41c10a4fb9a58fe1e6424fa2be |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T07:28:11Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-effc4e41c10a4fb9a58fe1e6424fa2be2023-11-17T07:30:22ZengMDPI AGDiagnostics2075-44182023-03-0113594810.3390/diagnostics13050948Transvaginal Ultrasound Accuracy in the Hydrosalpinx Diagnosis: A Systematic Review and Meta-AnalysisAina Delgado-Morell0Mar Nieto-Tous1Cristina Andrada-Ripollés2Maria Ángela Pascual3Silvia Ajossa4Stefano Guerriero5Juan Luis Alcázar6Department of Obstetrics and Gynecology, Hospital de la Santa Creu i Sant Pau, 08025 Barcelona, SpainDepartment of Obstetrics and Gynecology, Hospital Universitari i Politècnic La Fe, 46026 València, SpainDepartment of Obstetrics and Gynecology, Hospital General Universitari de Castelló, 12004 Castelló, SpainDepartment of Obstetrics, Gynecology and Reproduction, Hospital Universitari Dexeus, 08028 Barcelona, SpainCentro Integrato di Procreazione Medicalmente Assistita (PMA) e Diagnostica Ostetrico-Ginecologica, Azienda Ospedaliero Universitaria-Policlinico Duilio Casula, 09042 Monserrato, ItalyCentro Integrato di Procreazione Medicalmente Assistita (PMA) e Diagnostica Ostetrico-Ginecologica, Azienda Ospedaliero Universitaria-Policlinico Duilio Casula, 09042 Monserrato, ItalyDepartment of Obstetrics and Gynecology, School of Medicine, Universidad de Navarra, 31009 Pamplona, SpainHydrosalpinx is a condition with a crucial prognostic role in reproduction, and its diagnosis by a non-invasive technique such as ultrasound is key in achieving an adequate reproductive assessment while avoiding unnecessary laparoscopies. The aim of the present systematic review and meta-analysis is to synthetize and report the current evidence on transvaginal sonography (TVS) accuracy to diagnose hydrosalpinx. Articles on the topic published between January 1990 and December 2022 were searched in five electronic databases. Data from the six selected studies, comprising 4144 adnexal masses in 3974 women, 118 of which were hydrosalpinxes, were analyzed as follows: overall, TVS had a pooled estimated sensitivity for hydrosalpinx of 84% (95% confidence interval (CI) = 76–89%), specificity of 99% (95% CI = 98–100%), positive likelihood ratio of 80.7 (95% CI = 33.7–193.0), and negative likelihood ratio of 0.16 (95% CI = 0.11–0.25) and DOR of 496 (95% CI = 178–1381). The mean prevalence of hydrosalpinx was 4%. The quality of the studies and their risk of bias were assessed using QUADAS-2, evidencing an overall acceptable quality of the selected articles. We concluded that TVS has a good specificity and sensitivity for diagnosing hydrosalpinx.https://www.mdpi.com/2075-4418/13/5/948hydrosalpinxtransvaginal ultrasounddiagnosis |
| spellingShingle | Aina Delgado-Morell Mar Nieto-Tous Cristina Andrada-Ripollés Maria Ángela Pascual Silvia Ajossa Stefano Guerriero Juan Luis Alcázar Transvaginal Ultrasound Accuracy in the Hydrosalpinx Diagnosis: A Systematic Review and Meta-Analysis Diagnostics hydrosalpinx transvaginal ultrasound diagnosis |
| title | Transvaginal Ultrasound Accuracy in the Hydrosalpinx Diagnosis: A Systematic Review and Meta-Analysis |
| title_full | Transvaginal Ultrasound Accuracy in the Hydrosalpinx Diagnosis: A Systematic Review and Meta-Analysis |
| title_fullStr | Transvaginal Ultrasound Accuracy in the Hydrosalpinx Diagnosis: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Transvaginal Ultrasound Accuracy in the Hydrosalpinx Diagnosis: A Systematic Review and Meta-Analysis |
| title_short | Transvaginal Ultrasound Accuracy in the Hydrosalpinx Diagnosis: A Systematic Review and Meta-Analysis |
| title_sort | transvaginal ultrasound accuracy in the hydrosalpinx diagnosis a systematic review and meta analysis |
| topic | hydrosalpinx transvaginal ultrasound diagnosis |
| url | https://www.mdpi.com/2075-4418/13/5/948 |
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