Diverse Clinical Presentations of C3 Dominant Glomerulonephritis

Diverse Clinical Presentations of C3 Dominant Glomerulonephritis

C3 dominant immunofluorescence staining is present in a subset of patients with idiopathic immune complex membranoproliferative glomerulonephritis (iMPGN). It is increasingly recognized that iMPGN may be complement driven, as are cases of “typical” C3 glomerulopathy (C3G). In both iMPGN and C3G, a f...

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Bibliographic Details
Main Authors: Ramy M. Hanna, Jean Hou, Huma Hasnain, Farid Arman, Umut Selamet, James Wilson, Samuel Olanrewaju, Jonathan E. Zuckerman, Marina Barsoum, Julie M. Yabu, Ira Kurtz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Medicine
Subjects:
complement mutations
membranoproliferative glomerulonephritis
alternative pathway
C3 glomerulonephritis
proteinuria
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00293/full

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