Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury

Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury

Background. Ferroptosis plays a key role in cardiomyopathy. Atorvastatin (ATV) has a protective effect on ischemia-reperfusion (I/R) cardiomyopathy. The purpose of this study is to elucidate the mechanism of ATV in I/R injury. Methods. H9C2 cells and cardiomyopathy rats were induced by hypoxia/reoxy...

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Bibliographic Details
Main Authors:	You Peng, Bin Liao, Yan Zhou, Wei Zeng, Zhi-Yu Zeng
Format:	Article
Language:	English
Published:	Hindawi Limited 2022-01-01
Series:	Cardiology Research and Practice
Online Access:	http://dx.doi.org/10.1155/2022/3972829

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