Epithelioid sarcoma of femoral nerve: A case report
Introduction. Epithelioid sarcoma is a slow-growing malignant soft tissue tumor and occurs approximately in 1% of all soft tissue malignant tumors. This case report describes epithelioid sarcoma in femoral nerve and as we know it is the first described case of epithelioid sarcoma at this anatomical...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defence, Serbia
2018-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600350I.pdf |
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| author | Ivanov Dejan Živojinov Mirjana Ranisavljević Milan |
| author_facet | Ivanov Dejan Živojinov Mirjana Ranisavljević Milan |
| author_sort | Ivanov Dejan |
| collection | DOAJ |
| description | Introduction. Epithelioid sarcoma is a slow-growing malignant soft tissue tumor and occurs approximately in 1% of all soft tissue malignant tumors. This case report describes epithelioid sarcoma in femoral nerve and as we know it is the first described case of epithelioid sarcoma at this anatomical localisation. Case report. A 44-years-old female patient presented with strong pain in her left leg. On magnetic resonance imaging (MRI), tumor was presented as a node 8 cm in the diameter at left femoral nerve between ileopsoas and iliacus muscle, without infiltration of muscle fascia and tendons. Four enlarged lymph nodes described in left iliac fosa, were suspected on secondary tumor deposits. We preformed radical surgical excision of the tumor and femoral nerve transection with local lymp hnode disection. Histopathological analysis revealed epithelioid sarcoma, and tumor stained highly positive for anti-pan cytokeratin antibody (AE1/AE3), vimentin, cancer antigen 125 (CA125), anticytokeratin antibody (MNF116), hematopoietic progenitor cell antigen (CD34) and epithelial membrane antigen (EMA) markers. After the operation patient recived radiotherapy without chemotherapy. Six months postoperatively, there was no evidence of local relapses or distant metastases. Conclusion. Initial wide surgical resection and adjuvant radiotherapy is beneficial in treatment of epitheloid sarcoma. |
| first_indexed | 2024-12-23T13:14:23Z |
| format | Article |
| id | doaj.art-f009b839322a471a809a33b37c470e08 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 2406-0720 |
| language | English |
| last_indexed | 2025-03-14T13:08:31Z |
| publishDate | 2018-01-01 |
| publisher | Military Health Department, Ministry of Defence, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-f009b839322a471a809a33b37c470e082025-03-02T00:28:30ZengMilitary Health Department, Ministry of Defence, SerbiaVojnosanitetski Pregled0042-84502406-07202018-01-0175552152410.2298/VSP160819350I0042-84501600350IEpithelioid sarcoma of femoral nerve: A case reportIvanov Dejan0Živojinov Mirjana1Ranisavljević Milan2Clinical Center of Vojvodina, Clinic for Abdominal, Endocrine Surgery and Transplantation, Novi Sad + Clinical Center of Vojvodina, Department for Pathology, Novi SadClinical Center of Vojvodina, Department for Pathology, Novi Sad + Oncology Institute of Vojvodina, Sremska KamenicaClinical Center of Vojvodina, Department for Pathology, Novi Sad + Faculty of Medicine, Novi SadIntroduction. Epithelioid sarcoma is a slow-growing malignant soft tissue tumor and occurs approximately in 1% of all soft tissue malignant tumors. This case report describes epithelioid sarcoma in femoral nerve and as we know it is the first described case of epithelioid sarcoma at this anatomical localisation. Case report. A 44-years-old female patient presented with strong pain in her left leg. On magnetic resonance imaging (MRI), tumor was presented as a node 8 cm in the diameter at left femoral nerve between ileopsoas and iliacus muscle, without infiltration of muscle fascia and tendons. Four enlarged lymph nodes described in left iliac fosa, were suspected on secondary tumor deposits. We preformed radical surgical excision of the tumor and femoral nerve transection with local lymp hnode disection. Histopathological analysis revealed epithelioid sarcoma, and tumor stained highly positive for anti-pan cytokeratin antibody (AE1/AE3), vimentin, cancer antigen 125 (CA125), anticytokeratin antibody (MNF116), hematopoietic progenitor cell antigen (CD34) and epithelial membrane antigen (EMA) markers. After the operation patient recived radiotherapy without chemotherapy. Six months postoperatively, there was no evidence of local relapses or distant metastases. Conclusion. Initial wide surgical resection and adjuvant radiotherapy is beneficial in treatment of epitheloid sarcoma.http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600350I.pdfsarcomasoft tissue neoplasmsfemoral nervediagnostic techniques and proceduressurgical procedures, operativeradiotherapy |
| spellingShingle | Ivanov Dejan Živojinov Mirjana Ranisavljević Milan Epithelioid sarcoma of femoral nerve: A case report Vojnosanitetski Pregled sarcoma soft tissue neoplasms femoral nerve diagnostic techniques and procedures surgical procedures, operative radiotherapy |
| title | Epithelioid sarcoma of femoral nerve: A case report |
| title_full | Epithelioid sarcoma of femoral nerve: A case report |
| title_fullStr | Epithelioid sarcoma of femoral nerve: A case report |
| title_full_unstemmed | Epithelioid sarcoma of femoral nerve: A case report |
| title_short | Epithelioid sarcoma of femoral nerve: A case report |
| title_sort | epithelioid sarcoma of femoral nerve a case report |
| topic | sarcoma soft tissue neoplasms femoral nerve diagnostic techniques and procedures surgical procedures, operative radiotherapy |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600350I.pdf |
| work_keys_str_mv | AT ivanovdejan epithelioidsarcomaoffemoralnerveacasereport AT zivojinovmirjana epithelioidsarcomaoffemoralnerveacasereport AT ranisavljevicmilan epithelioidsarcomaoffemoralnerveacasereport |