The effect of Teucrium polium capsules on the trend of primary dysmenorrhea using pair copula Bayesian network

Introduction: Primary dysmenorrhea is one of the common causes of decreased efficiency at work, education, and reduced quality of life in women. Therefore, this study was performed with aim to determine the effect of Teucrium polium L. capsules on the changes of pain intensity and duration among pat...

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Main Authors: Mohamad Reza Pourahmdi, Yadollah Mehrabi, zohreh keshavarz, Khadije Abadian, Zahra Shirmohamadi Hesari
Format: Article
Language:fas
Published: Mashhad University of Medical Sciences 2019-05-01
Series:Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Subjects:
Online Access:https://ijogi.mums.ac.ir/article_13389_b30a0f656eb2c68b252bfe71e43c6510.pdf
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author Mohamad Reza Pourahmdi
Yadollah Mehrabi
zohreh keshavarz
Khadije Abadian
Zahra Shirmohamadi Hesari
author_facet Mohamad Reza Pourahmdi
Yadollah Mehrabi
zohreh keshavarz
Khadije Abadian
Zahra Shirmohamadi Hesari
author_sort Mohamad Reza Pourahmdi
collection DOAJ
description Introduction: Primary dysmenorrhea is one of the common causes of decreased efficiency at work, education, and reduced quality of life in women. Therefore, this study was performed with aim to determine the effect of Teucrium polium L. capsules on the changes of pain intensity and duration among patients with primary dysmenorrhea. Methods: This triple-blind, controlled, randomized clinical trial was performed on 70 female students with primary dysmenorrhea in selected dormitories of Shahid Beheshti University in 2014. The subjects were randomly divided in two intervention and control groups. During first three days of menstrual period, the intervention group was treated with Teucrium polium L. capsules every 6 hours, and the control group received the starch powder capsules during two consequent months. The associations between duration and intensity of dysmenorrhea pain in different time periods were determined based on Bayesian network and data were analyzed statistically using Pair-copulas. Data analysis was performed using SPSS software (version 20) and R (versions 1, 3, 4 (and independent t test, Mann-Whitney test, and pair-copula Bayesian network model. Results: Given the fitting model, the patients who experienced high-intensive pain before the intervention had very high decrease of pain during the first month using Teucrium polium L. capsules (λ1=0). In the subjects with the lowest pain duration (3 days), there was no significant effect after using capsules in the first month (λ1=0.51, λu=0.51), but the significant effect of capsules was recorded in the second month for these patients. Conclusion: Teucrium polium capsule can be considered one of the drugs with high effect for the treatment of primary dysmenorrhea, because this drug has very high decreasing effect for patients who suffer from intensive and long duration menstrual pain.
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spelling doaj.art-f009c7fda9674650b33c14d64e1c875e2022-12-22T02:41:19ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632019-05-01223414810.22038/ijogi.2019.1338913389The effect of Teucrium polium capsules on the trend of primary dysmenorrhea using pair copula Bayesian networkMohamad Reza Pourahmdi0Yadollah Mehrabi1zohreh keshavarz2Khadije Abadian3Zahra Shirmohamadi Hesari4M.Sc. in Biostatistics, School of Paramedicine, Shahid Beheshti University of Medical Science, Tehran, Iran.Professor, Department of Epidemiology, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Associate professor, Department of Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.PhD student in Reproductive Health, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.M.Sc. in Biostatistics, School of Paramedicine, Shahid Beheshti University of Medical Science, Tehran, Iran.Introduction: Primary dysmenorrhea is one of the common causes of decreased efficiency at work, education, and reduced quality of life in women. Therefore, this study was performed with aim to determine the effect of Teucrium polium L. capsules on the changes of pain intensity and duration among patients with primary dysmenorrhea. Methods: This triple-blind, controlled, randomized clinical trial was performed on 70 female students with primary dysmenorrhea in selected dormitories of Shahid Beheshti University in 2014. The subjects were randomly divided in two intervention and control groups. During first three days of menstrual period, the intervention group was treated with Teucrium polium L. capsules every 6 hours, and the control group received the starch powder capsules during two consequent months. The associations between duration and intensity of dysmenorrhea pain in different time periods were determined based on Bayesian network and data were analyzed statistically using Pair-copulas. Data analysis was performed using SPSS software (version 20) and R (versions 1, 3, 4 (and independent t test, Mann-Whitney test, and pair-copula Bayesian network model. Results: Given the fitting model, the patients who experienced high-intensive pain before the intervention had very high decrease of pain during the first month using Teucrium polium L. capsules (λ1=0). In the subjects with the lowest pain duration (3 days), there was no significant effect after using capsules in the first month (λ1=0.51, λu=0.51), but the significant effect of capsules was recorded in the second month for these patients. Conclusion: Teucrium polium capsule can be considered one of the drugs with high effect for the treatment of primary dysmenorrhea, because this drug has very high decreasing effect for patients who suffer from intensive and long duration menstrual pain.https://ijogi.mums.ac.ir/article_13389_b30a0f656eb2c68b252bfe71e43c6510.pdfpair-copulaprimary dysmenorrheatail dependenceteucrium polium
spellingShingle Mohamad Reza Pourahmdi
Yadollah Mehrabi
zohreh keshavarz
Khadije Abadian
Zahra Shirmohamadi Hesari
The effect of Teucrium polium capsules on the trend of primary dysmenorrhea using pair copula Bayesian network
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
pair-copula
primary dysmenorrhea
tail dependence
teucrium polium
title The effect of Teucrium polium capsules on the trend of primary dysmenorrhea using pair copula Bayesian network
title_full The effect of Teucrium polium capsules on the trend of primary dysmenorrhea using pair copula Bayesian network
title_fullStr The effect of Teucrium polium capsules on the trend of primary dysmenorrhea using pair copula Bayesian network
title_full_unstemmed The effect of Teucrium polium capsules on the trend of primary dysmenorrhea using pair copula Bayesian network
title_short The effect of Teucrium polium capsules on the trend of primary dysmenorrhea using pair copula Bayesian network
title_sort effect of teucrium polium capsules on the trend of primary dysmenorrhea using pair copula bayesian network
topic pair-copula
primary dysmenorrhea
tail dependence
teucrium polium
url https://ijogi.mums.ac.ir/article_13389_b30a0f656eb2c68b252bfe71e43c6510.pdf
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