Enzymatic synthesis of high-titer nicotinamide mononucleotide with a new nicotinamide riboside kinase and an efficient ATP regeneration system

Enzymatic synthesis of high-titer nicotinamide mononucleotide with a new nicotinamide riboside kinase and an efficient ATP regeneration system

Abstract Background β-Nicotinamide mononucleotide (NMN) is the direct precursor of nicotinamide coenzymes such as NAD+ and NADP+, which are widely applied in industrial biocatalysis especially involving cofactor-dependent oxidoreductases. Moreover, NMN is a promising candidate for medical uses since...

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Bibliographic Details
Main Authors: Xiao-Long Qian, Yi-Si Dai, Chun-Xiu Li, Jiang Pan, Jian-He Xu, Bozhong Mu
Format: Article
Language:English
Published: SpringerOpen 2022-03-01
Series:Bioresources and Bioprocessing
Subjects:
Enzymatic phosphorylation
Nicotinamide riboside
Nicotinamide riboside kinase
β-Nicotinamide mononucleotide (NMN)
ATP regeneration system
Online Access:https://doi.org/10.1186/s40643-022-00514-6

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