The prevalence of antibodies against the HLA-DRB3 protein in kidney transplantation and the correlation with HLA expression.

The prevalence of antibodies against the HLA-DRB3 protein in kidney transplantation and the correlation with HLA expression.

Human leukocyte antigen (HLA)-DRB3 is a functional HLA class II gene, which has a limited allele diversity in the human population. Furthermore, the HLA-DRB3 gene is only present in a subset of individuals. Therefore, in organ transplantation, this HLA molecule is frequently mismatched between patie...

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Main Authors: Thomas H P M Habets, Bouke G Hepkema, Niels Kouprie, Melanie C A Schnijderberg, Tim C van Smaalen, Laura B Bungener, Maarten H L Christiaans, Gerard M J Bos, Joris Vanderlocht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6128541?pdf=render

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