Obstetric determinants of preterm delivery in a regional hospital, Accra, Ghana 2016

Abstract Background Globally, prematurity is a major determinant of morbidity and mortality contributing 30–40% of neonatal mortality. The consequences of preterm deliveries are enormous with developmental and childhood complications as well as high economic and psycho-social burden on the parents (...

Full description

Bibliographic Details
Main Authors: Ernest Konadu Aseidu, Delia Akosua Bandoh, Donne Kofi Ameme, Priscilla Nortey, Patricia Akweongo, Samuel Oko Sackey, Edwin Afari, Kofi Mensah Nyarko, Ernest Kenu
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Pregnancy and Childbirth
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12884-019-2404-6
_version_ 1828157368684249088
author Ernest Konadu Aseidu
Delia Akosua Bandoh
Donne Kofi Ameme
Priscilla Nortey
Patricia Akweongo
Samuel Oko Sackey
Edwin Afari
Kofi Mensah Nyarko
Ernest Kenu
author_facet Ernest Konadu Aseidu
Delia Akosua Bandoh
Donne Kofi Ameme
Priscilla Nortey
Patricia Akweongo
Samuel Oko Sackey
Edwin Afari
Kofi Mensah Nyarko
Ernest Kenu
author_sort Ernest Konadu Aseidu
collection DOAJ
description Abstract Background Globally, prematurity is a major determinant of morbidity and mortality contributing 30–40% of neonatal mortality. The consequences of preterm deliveries are enormous with developmental and childhood complications as well as high economic and psycho-social burden on the parents (family) and society. Some risk factors include ever having preterm delivery, multiple births and some medical conditions like sexually transmitted infection and urinary tract infections but these have not been ascertained in our study area. Much research into these risk factors is needed in Ghana. We assessed the obstetric determinants of preterm delivery. Methods We conducted a 1:2 unmatched case-control study in Greater Accra Regional Hospital (GARH) -Ridge, a secondary referral facility in Accra, Ghana (from October, 2015 -May, 2016). A case was a mother who delivered between 28 and 36 weeks of gestation (preterm) and a control was a mother who delivered after 37 to 42 completed weeks (term). We used structured questionnaire to collect data, reviewed maternal and foetal records using a checklist. Categorical variables were analysed and expressed as frequencies and proportions. We determined the association between obstetric factors and preterm delivery with multiple logistic regression. Significance level of the strength of association was determined at 95% CI and p-value < 0.05. Results We recruited 390 mothers, 130 had preterm deliveries (cases) and 260 had term deliveries (controls). Experiencing premature rupture of membrane (aOR: 2.3; 95% CI:1.0–5.5), pre-eclampsia/eclampsia (aOR: 3.4; 95% CI: 1.0–11.9) were found to be associated with preterm delivery. However, four or more ANC visit was protective factor for preterm delivery (aOR: 0.2; 95% CI: 0.1–0.4). Conclusion Premature rupture of membrane, hypertensive complications and antepartum haemorrhage were found to be risk factors associated with preterm delivery in Ridge Hospital. Health workforce providing ANC services need to identify risk factors and refer these mothers to the doctor for early management and improved outcome decreasing preterm delivery.
first_indexed 2024-04-11T23:27:07Z
format Article
id doaj.art-f0154e6ea3624ca3a5e028d1ff5876ec
institution Directory Open Access Journal
issn 1471-2393
language English
last_indexed 2024-04-11T23:27:07Z
publishDate 2019-07-01
publisher BMC
record_format Article
series BMC Pregnancy and Childbirth
spelling doaj.art-f0154e6ea3624ca3a5e028d1ff5876ec2022-12-22T03:57:16ZengBMCBMC Pregnancy and Childbirth1471-23932019-07-011911810.1186/s12884-019-2404-6Obstetric determinants of preterm delivery in a regional hospital, Accra, Ghana 2016Ernest Konadu Aseidu0Delia Akosua Bandoh1Donne Kofi Ameme2Priscilla Nortey3Patricia Akweongo4Samuel Oko Sackey5Edwin Afari6Kofi Mensah Nyarko7Ernest Kenu8Ghana Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, University of GhanaGhana Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, University of GhanaGhana Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, University of GhanaGhana Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, University of GhanaGhana Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, University of GhanaGhana Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, University of GhanaGhana Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, University of GhanaNamibia Field Epidemiology and Laboratory Training Programme, University of NamibiaGhana Field Epidemiology and Laboratory Training Programme, Department of Epidemiology and Disease Control, School of Public Health, University of GhanaAbstract Background Globally, prematurity is a major determinant of morbidity and mortality contributing 30–40% of neonatal mortality. The consequences of preterm deliveries are enormous with developmental and childhood complications as well as high economic and psycho-social burden on the parents (family) and society. Some risk factors include ever having preterm delivery, multiple births and some medical conditions like sexually transmitted infection and urinary tract infections but these have not been ascertained in our study area. Much research into these risk factors is needed in Ghana. We assessed the obstetric determinants of preterm delivery. Methods We conducted a 1:2 unmatched case-control study in Greater Accra Regional Hospital (GARH) -Ridge, a secondary referral facility in Accra, Ghana (from October, 2015 -May, 2016). A case was a mother who delivered between 28 and 36 weeks of gestation (preterm) and a control was a mother who delivered after 37 to 42 completed weeks (term). We used structured questionnaire to collect data, reviewed maternal and foetal records using a checklist. Categorical variables were analysed and expressed as frequencies and proportions. We determined the association between obstetric factors and preterm delivery with multiple logistic regression. Significance level of the strength of association was determined at 95% CI and p-value < 0.05. Results We recruited 390 mothers, 130 had preterm deliveries (cases) and 260 had term deliveries (controls). Experiencing premature rupture of membrane (aOR: 2.3; 95% CI:1.0–5.5), pre-eclampsia/eclampsia (aOR: 3.4; 95% CI: 1.0–11.9) were found to be associated with preterm delivery. However, four or more ANC visit was protective factor for preterm delivery (aOR: 0.2; 95% CI: 0.1–0.4). Conclusion Premature rupture of membrane, hypertensive complications and antepartum haemorrhage were found to be risk factors associated with preterm delivery in Ridge Hospital. Health workforce providing ANC services need to identify risk factors and refer these mothers to the doctor for early management and improved outcome decreasing preterm delivery.http://link.springer.com/article/10.1186/s12884-019-2404-6Preterm deliveryUnmatched case-controlObstetric factors
spellingShingle Ernest Konadu Aseidu
Delia Akosua Bandoh
Donne Kofi Ameme
Priscilla Nortey
Patricia Akweongo
Samuel Oko Sackey
Edwin Afari
Kofi Mensah Nyarko
Ernest Kenu
Obstetric determinants of preterm delivery in a regional hospital, Accra, Ghana 2016
BMC Pregnancy and Childbirth
Preterm delivery
Unmatched case-control
Obstetric factors
title Obstetric determinants of preterm delivery in a regional hospital, Accra, Ghana 2016
title_full Obstetric determinants of preterm delivery in a regional hospital, Accra, Ghana 2016
title_fullStr Obstetric determinants of preterm delivery in a regional hospital, Accra, Ghana 2016
title_full_unstemmed Obstetric determinants of preterm delivery in a regional hospital, Accra, Ghana 2016
title_short Obstetric determinants of preterm delivery in a regional hospital, Accra, Ghana 2016
title_sort obstetric determinants of preterm delivery in a regional hospital accra ghana 2016
topic Preterm delivery
Unmatched case-control
Obstetric factors
url http://link.springer.com/article/10.1186/s12884-019-2404-6
work_keys_str_mv AT ernestkonaduaseidu obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016
AT deliaakosuabandoh obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016
AT donnekofiameme obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016
AT priscillanortey obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016
AT patriciaakweongo obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016
AT samuelokosackey obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016
AT edwinafari obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016
AT kofimensahnyarko obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016
AT ernestkenu obstetricdeterminantsofpretermdeliveryinaregionalhospitalaccraghana2016