Efficacy of aluminum chloride in severe regorafenib-associated hand-foot skin reactions: a single-arm trial

Efficacy of aluminum chloride in severe regorafenib-associated hand-foot skin reactions: a single-arm trial

Abstract Background Regorafenib, a multikinase inhibitor, causes a high frequency of hand-foot skin reactions (HFSRs). The present study evaluated the efficacy of topical aluminum chloride, a perspiration suppressant, in reducing the severity of hand-foot skin reactions (HFSRs) caused by regorafenib...

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Main Authors: Aya Nishizawa, Eiji Shinozaki, Takeru Wakatsuki, Takahiro Satoh, Naoya Yamazaki, Shunsuke Oyamada, Keisuke Ariyoshi, Kota Kihara, Masahiro Tsuboi, Kensei Yamaguchi
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cancer
Subjects:
Hand-foot skin reactions
Multi kinase inhibitors
Regorafenib
Aluminum chloride
Online Access:https://doi.org/10.1186/s12885-023-10864-9

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