Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle “OP7”

Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle “OP7”

Summary: Defective interfering particles (DIPs) are regarded as potent broad-spectrum antivirals. We developed a mathematical model that describes intracellular co-infection dynamics of influenza standard virus (STV) and “OP7”, a new type of influenza DIP discovered recently. Based on experimental d...

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Bibliographic Details
Main Authors:	Daniel Rüdiger, Julita Piasecka, Jan Küchler, Carolina Pontes, Tanja Laske, Sascha Y. Kupke, Udo Reichl
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Series:	iScience
Subjects:	Biological sciences Biological sciences research methodologies Natural sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224006424

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