The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-Analysis
Background: Cardiac rehabilitation (CR) is a multidisciplinary medical program. Most studies have emphasized the effect of exercise-based CR in lowering lipid levels; however, the effect of CR as a comprehensive program on lipid levels remains unclear. Methods: Electronic database were searched up t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ubiquity Press
2022-11-01
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| Series: | Global Heart |
| Subjects: | |
| Online Access: | https://globalheartjournal.com/articles/1170 |
| _version_ | 1811178215426752512 |
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| author | Gang Wu Yemei Hu Kun Ding Xuedong Li Jun Li Zhuo Shang |
| author_facet | Gang Wu Yemei Hu Kun Ding Xuedong Li Jun Li Zhuo Shang |
| author_sort | Gang Wu |
| collection | DOAJ |
| description | Background: Cardiac rehabilitation (CR) is a multidisciplinary medical program. Most studies have emphasized the effect of exercise-based CR in lowering lipid levels; however, the effect of CR as a comprehensive program on lipid levels remains unclear. Methods: Electronic database were searched up to 2022. Randomized controlled trials with lipid profile indicators were included. Standardized mean differences (SMDs) and 95% CIs were used to evaluate the effect size. Begg’s funnel plot and Egger’s linear regression test were used to assess publication bias. Results: CR remarkably reduced low-density lipoprotein cholesterol (LDL-C) levels (SMD = –0.23; 95%CI: [–0.38, –0.08]; P < 0.001), triglyceride (TG) levels (SMD = –0.17; 95%CI: [–0.28, –0.06]; P < 0.001), and total cholesterol (TC) levels (SMD = –0.30; 95%CI: [–0.43, –0.16]; P < 0.001) and increased high-density lipoprotein cholesterol (HDL-C) levels (SMD = 0.19; 95%CI: [0.10, 0.29]; P < 0.001). Conclusions: CR reduce TC, TG, and LDL-C levels while improving HDL-C levels. CR should be promoted and more trials should be conducted for long-term CR. |
| first_indexed | 2024-04-11T06:14:43Z |
| format | Article |
| id | doaj.art-f01976930ad3411da9547ab85f378e6d |
| institution | Directory Open Access Journal |
| issn | 2211-8179 |
| language | English |
| last_indexed | 2024-04-11T06:14:43Z |
| publishDate | 2022-11-01 |
| publisher | Ubiquity Press |
| record_format | Article |
| series | Global Heart |
| spelling | doaj.art-f01976930ad3411da9547ab85f378e6d2022-12-22T04:41:06ZengUbiquity PressGlobal Heart2211-81792022-11-0117110.5334/gh.1170991The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-AnalysisGang Wu0Yemei Hu1Kun Ding2Xuedong Li3Jun Li4Zhuo Shang5Department of Cardiology, Bengbu second people’s hospital, Bengbu, Anhui province, 233000Department of Cardiology, Bengbu second people’s hospital, Bengbu, Anhui province, 233000Department of Cardiology, Bengbu second people’s hospital, Bengbu, Anhui province, 233000Department of Cardiology, Bengbu second people’s hospital, Bengbu, Anhui province, 233000Department of Cardiology, Bengbu second people’s hospital, Bengbu, Anhui province, 233000Bengbu second people’s hospital, No. 302 of Yan’ an Road, Bengbu, Anhui province, 233000Background: Cardiac rehabilitation (CR) is a multidisciplinary medical program. Most studies have emphasized the effect of exercise-based CR in lowering lipid levels; however, the effect of CR as a comprehensive program on lipid levels remains unclear. Methods: Electronic database were searched up to 2022. Randomized controlled trials with lipid profile indicators were included. Standardized mean differences (SMDs) and 95% CIs were used to evaluate the effect size. Begg’s funnel plot and Egger’s linear regression test were used to assess publication bias. Results: CR remarkably reduced low-density lipoprotein cholesterol (LDL-C) levels (SMD = –0.23; 95%CI: [–0.38, –0.08]; P < 0.001), triglyceride (TG) levels (SMD = –0.17; 95%CI: [–0.28, –0.06]; P < 0.001), and total cholesterol (TC) levels (SMD = –0.30; 95%CI: [–0.43, –0.16]; P < 0.001) and increased high-density lipoprotein cholesterol (HDL-C) levels (SMD = 0.19; 95%CI: [0.10, 0.29]; P < 0.001). Conclusions: CR reduce TC, TG, and LDL-C levels while improving HDL-C levels. CR should be promoted and more trials should be conducted for long-term CR.https://globalheartjournal.com/articles/1170coronary diseasecoronary disease rehabilitationlipid profilerandomized controlled trials |
| spellingShingle | Gang Wu Yemei Hu Kun Ding Xuedong Li Jun Li Zhuo Shang The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-Analysis Global Heart coronary disease coronary disease rehabilitation lipid profile randomized controlled trials |
| title | The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-Analysis |
| title_full | The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-Analysis |
| title_fullStr | The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-Analysis |
| title_full_unstemmed | The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-Analysis |
| title_short | The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-Analysis |
| title_sort | effect of cardiac rehabilitation on lipid levels in patients with coronary heart disease a systematic review and meta analysis |
| topic | coronary disease coronary disease rehabilitation lipid profile randomized controlled trials |
| url | https://globalheartjournal.com/articles/1170 |
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