BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease

BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease

Peripheral artery disease (PAD) is characterized by impaired blood flow to the lower extremities, resulting in ischemic limb injuries. Individuals with diabetes and PAD typically have more severe ischemic limb injuries and limb amputations, but the mechanisms involved are poorly understood. Previous...

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Bibliographic Details
Main Authors: Arul M. Mani, Karthik Dhanabalan, Victor Lamin, Thomas Wong, Madhu V. Singh, Ayotunde O. Dokun
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
BAG3
peripheral artery disease
diabetes
autophagy
necroptosis
Online Access:https://www.mdpi.com/1422-0067/23/18/10715

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